Evidence map›Paper›PMID 28149506›Full record

ReviewF1000Research2017

Treatment of Hypogonadism: Current and Future Therapies.

Arthi Thirumalai, Kathryn E Berkseth, John K Amory

Open access · goldAbstract readReview
In one paragraph

Review in F1000Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
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  16. Review
  17. Direct conversion of human fibroblasts into functional Leydig-like cells byAmerican journal of translational research · 2018
    Article
  18. Estrogens and Body Weight Regulation in Men.Advances in experimental medicine and biology · 2017
    Review
  19. Compounded bioidentical hormone products, a path forward.Journal of the American Pharmacists Association : JAPhA
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Arthi ThirumalaiDivision of Metabolism, Endocrinology, and Nutrition, Department of Medicine, University of Washington, Seattle, WA, USA.
Kathryn E BerksethDivision of Metabolism, Endocrinology, and Nutrition, Department of Medicine, University of Washington, Seattle, WA, USA.
John K AmoryCenter for Research in Reproduction and Contraception, Department of Medicine, University of Washington, Seattle, WA, USA.
University of Washington · US

Funding

Diabetes, Obesity and Metabolism Training ProgramT32DK007247 · NIDDK · UNIVERSITY OF WASHINGTON · PI GREGORY J MORTON, KRISTINA Marie UTZSCHNEIDER · 1986 to 2026
$10.0M
Retinoic Acid in Male InfertilityK24HD082231 · NICHD · UNIVERSITY OF WASHINGTON · PI AMORY, JOHN K. · 2015 to 2019
$638k
NICHD NIH HHS K24 HD082231NIDDK NIH HHS T32 DK007247
6 · The paper itself

Abstract

The treatment of hypogonadism in men is of great interest to both patients and providers. There are a number of testosterone formulations currently available and several additional formulations under development. In addition, there are some lesser-used alternative therapies for the management of male hypogonadism, which may have advantages for certain patient groups. The future of hypogonadism therapy may lie in the development of selective androgen receptor modulators that allow the benefits of androgens whilst minimizing unwanted side effects.

Indexed as

aromatase inhibitordihydrotestosterone gelhypogonadismselective androgen receptor modulatortestosterone therapy

Identifiers

PMID28149506
PMCPMC5265703
OpenAlexW2581728484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.