Evidence map›Paper›PMID 28149050›Full record

ArticleBioinformation2016

Insights using the molecular model of Lipoxygenase from Finger millet (Eleusine coracana (L.)).

Apoorv Tiwari, Himanshu Avashthi, Richa Jha, Ambuj Srivastava, Vijay Kumar Garg, Pramod Wasudev Ramteke, Anil Kumar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioinformation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Biosynthesis of (R)-(-)-1-Octen-3-ol in RecombinantJournal of microbiology and biotechnology · 2020
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Apoorv Tiwari *Department of Molecular Biology & Genetic Engineering, CBSH, G. B. Pant University of Agriculture & Technology, Pantnagar-263145,Uttarakhand, Bharat (India).
Himanshu Avashthi *Department of Molecular Biology & Genetic Engineering, CBSH, G. B. Pant University of Agriculture & Technology, Pantnagar-263145,Uttarakhand, Bharat (India).
Richa Jha *Uttaranchal Institute of Technology, Uttaranchal University, Arcadia Grant, Dehradun-248007, Uttarakhand Bharat (India).
Ambuj Srivastava *Department of Biotechnology, Indian Institute of Technology Madras, Chennai-600036, Tamil Nadu, Bharat (India).
Vijay Kumar Garg *Department of Molecular Biology & Genetic Engineering, CBSH, G. B. Pant University of Agriculture & Technology, Pantnagar-263145,Uttarakhand, Bharat (India).
Pramod Wasudev Ramteke *Department of Biological Science, School of Basic Science, Sam Higginbottom Institute of Agriculture, Technology and Sciences, Allahabad-211007, Uttar Pradesh, Bharat (India).
Anil Kumar *Department of Molecular Biology & Genetic Engineering, CBSH, G. B. Pant University of Agriculture & Technology, Pantnagar-263145,Uttarakhand, Bharat (India).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipoxygenase-1 (LOX-1) protein provides defense against pests and pathogens and its presence have been positively correlated with plant resistance against pathogens. Linoleate is a known substrate of lipoxygenase and it induces necrosis leading to the accumulation of isoflavonoid phytoalexins in plant leaves. Therefore, it is of interest to study the structural features of LOX-1 from Finger millet. However, the structure ofLOX-1 from Finger millet is not yet known. A homology model of LOX-1 from Finger millet is described. Domain architecture study suggested the presence of two domains namely PLAT (Phospho Lipid Acyl Transferase) and lipoxygenase. Molecular docking models of linoleate with lipoxygenase from finger millet, rice and sorghum are reported. The features of docked models showed that finger millet have higher pathogen resistance in comparison to other cereal crops. This data is useful for the molecular cloning of fulllength LOX-1 gene for validating its role in improving plant defense against pathogen infection and for various other biological processes.

Indexed as

dockingEleusine coracanahomology modelingLipoxygenasepest resistanceprotein-protein interactionStructure prediction

Identifiers

PMID28149050
PMCPMC5267959

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.