Evidence map›Paper›PMID 28148827›Full record

ArticleMolecular cancer research : MCR2017

Mutant IDH1 Disrupts the Mouse Subventricular Zone and Alters Brain Tumor Progression.

Christopher J Pirozzi, Austin B Carpenter, Matthew S Waitkus, Catherine Y Wang, Huishan Zhu, Landon J Hansen, Lee H Chen, Paula K Greer, Jie Feng, Yu Wang and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in Molecular cancer research : MCR, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Glioma.Nature reviews. Disease primers · 2024
    Review
  7. Article
  8. Radiosynthesis and biological evaluation of [European journal of nuclear medicine and molecular imaging · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. The Significance ofInternational journal of molecular sciences · 2022
    Observational
  14. Article
  15. The epigenetic dysfunction underlying malignant glioma pathogenesis.Laboratory investigation; a journal of technical methods and pathology · 2022
    Review
  16. Impact ofBiomedicines · 2022
    Article
  17. Review
  18. Review
  19. Association ofCells · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

Christopher J PirozziThe Preston Robert Tisch Brain Tumor Center at Duke, Department of Pathology, Duke University Medical Center, Durham, North Carolina.
Austin B CarpenterThe Preston Robert Tisch Brain Tumor Center at Duke, Department of Pathology, Duke University Medical Center, Durham, North Carolina.
Matthew S WaitkusThe Preston Robert Tisch Brain Tumor Center at Duke, Department of Pathology, Duke University Medical Center, Durham, North Carolina.
Catherine Y WangThe Preston Robert Tisch Brain Tumor Center at Duke, Department of Pathology, Duke University Medical Center, Durham, North Carolina.
Huishan ZhuThe Preston Robert Tisch Brain Tumor Center at Duke, Department of Pathology, Duke University Medical Center, Durham, North Carolina.
Landon J HansenThe Preston Robert Tisch Brain Tumor Center at Duke, Department of Pathology, Duke University Medical Center, Durham, North Carolina.
Lee H ChenThe Preston Robert Tisch Brain Tumor Center at Duke, Department of Pathology, Duke University Medical Center, Durham, North Carolina.
Paula K GreerThe Preston Robert Tisch Brain Tumor Center at Duke, Department of Pathology, Duke University Medical Center, Durham, North Carolina.
Jie FengBeijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Yu WangNeurosurgery Department, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Cheryl B BockDuke Cancer Institute, Duke University Medical Center, Durham, North Carolina.
Ping FanDuke Cancer Institute, Duke University Medical Center, Durham, North Carolina.
Ivan SpasojevicDuke Cancer Institute, Duke University Medical Center, Durham, North Carolina.
Roger E McLendonThe Preston Robert Tisch Brain Tumor Center at Duke, Department of Pathology, Duke University Medical Center, Durham, North Carolina.
Darell D BignerThe Preston Robert Tisch Brain Tumor Center at Duke, Department of Pathology, Duke University Medical Center, Durham, North Carolina.
Yiping HeThe Preston Robert Tisch Brain Tumor Center at Duke, Department of Pathology, Duke University Medical Center, Durham, North Carolina. yiping.he@duke.edu hai.yan@duke.edu.
Hai YanThe Preston Robert Tisch Brain Tumor Center at Duke, Department of Pathology, Duke University Medical Center, Durham, North Carolina. yiping.he@duke.edu hai.yan@duke.edu.
Duke University · USDuke Medical Center · USBeijing Institute of Neurosurgery · CNBeijing Tian Tan Hospital · CN

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007171 · NIGMS · DUKE UNIVERSITY · PI KONTOS, CHRISTOPHER D · 1985 to 2021
$31.2M
ORGANIZATION AND FUNCTIONS OF CELLULAR STRUCTUREST32GM007184 · NIGMS · DUKE UNIVERSITY · PI JINKS-ROBERTSON, SUE · 1985 to 2019
$18.2M
The Role of IDH1 Mutations in Gliomagenesis and MetabolismR01CA140316 · NCI · DUKE UNIVERSITY · PI YAN, HAI · 2010 to 2019
$3.2M
NCI NIH HHS R01 CA140316NIGMS NIH HHS T32 GM007171NIGMS NIH HHS T32 GM007184
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MutationAnimalsBrain NeoplasmsCell DifferentiationCell ProliferationCells, CulturedDNA MethylationGene Knock-In TechniquesHumansIsocitrate DehydrogenaseLateral VentriclesMiceMice, TransgenicNeural Stem CellsOligodendrocyte Transcription Factor 2Promoter Regions, GeneticIDH1 protein, humanIsocitrate DehydrogenaseOlig2 protein, mouseOligodendrocyte Transcription Factor 2

Identifiers

PMID28148827
PMCPMC5415422
OpenAlexW2584285792

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.