Evidence map›Paper›PMID 28148802›Full record

ArticleJournal of virology2017

Recombinant Isfahan Virus and Vesicular Stomatitis Virus Vaccine Vectors Provide Durable, Multivalent, Single-Dose Protection against Lethal Alphavirus Challenge.

Farooq Nasar, Demetrius Matassov, Robert L Seymour, Theresa Latham, Rodion V Gorchakov, Rebecca M Nowak, Grace Leal, Stefan Hamm, John H Eldridge, Robert B Tesh and 2 more

Abstract read
In one paragraph

Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Clinical and Immunological Effects of p53-Targeting Vaccines.Frontiers in cell and developmental biology · 2021
    Review
  8. Vaccination against the Epstein-Barr virus.Cellular and molecular life sciences : CMLS · 2020
    Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Tick-Borne Viruses.Virologica Sinica · 2018
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Farooq NasarInstitute for Human Infections and Immunity, Center for Tropical Diseases, and Departments of Pathology and Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA fanasar@icloud.com sweaver@utmb.edu.
Demetrius MatassovProfectus BioSciences Inc., Tarrytown, New York, USA.
Robert L SeymourInstitute for Human Infections and Immunity, Center for Tropical Diseases, and Departments of Pathology and Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA.
Theresa LathamProfectus BioSciences Inc., Tarrytown, New York, USA.
Rodion V GorchakovDepartment of Pediatrics, Section of Tropical Medicine, Baylor College of Medicine, Houston, Texas, USA.
Rebecca M NowakProfectus BioSciences Inc., Tarrytown, New York, USA.
Grace LealInstitute for Human Infections and Immunity, Center for Tropical Diseases, and Departments of Pathology and Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA.
Stefan HammProfectus BioSciences Inc., Tarrytown, New York, USA.
John H EldridgeProfectus BioSciences Inc., Tarrytown, New York, USA.
Robert B TeshInstitute for Human Infections and Immunity, Center for Tropical Diseases, and Departments of Pathology and Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA.
David K ClarkeProfectus BioSciences Inc., Tarrytown, New York, USA.
Scott C WeaverInstitute for Human Infections and Immunity, Center for Tropical Diseases, and Departments of Pathology and Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA fanasar@icloud.com sweaver@utmb.edu.

Funding

World Reference Center for Emerging Viruses and Arboviruses (WRCEVA)R24AI120942 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI WEAVER, SCOTT C · 2016 to 2024
$8.5M
NIAID NIH HHS R24 AI120942
6 · The paper itself

Abstract

The demonstrated clinical efficacy of a recombinant vesicular stomatitis virus (rVSV) vaccine vector has stimulated the investigation of additional serologically distinct

Indexed as

Drug CarriersAnimalsAntibodies, NeutralizingAntibodies, ViralDisease Models, AnimalEncephalitis Virus, Eastern EquineEncephalitis Virus, Venezuelan EquineEncephalomyelitis, EquineGlycoproteinsMembrane ProteinsMiceSurvival AnalysisVaccines, SyntheticVesiculovirusViral VaccinesAntibodies, NeutralizingAntibodies, ViralDrug CarriersGlycoproteinsMembrane ProteinsVaccines, SyntheticViral VaccinesEastern equine encephalitis virusIsfahan virusVenezuelan equine encephalitis virusvesicular stomatitis virus

Identifiers

PMID28148802
PMCPMC5375677

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.