Evidence map›Paper›PMID 28148777›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2017

Sabotaging of the oxidative stress response by an oncogenic noncoding RNA.

Nitin Mahajan, Hua-Jun Wu, Richard L Bennett, Catalina Troche, Jonathan D Licht, Jason D Weber, Leonard B Maggi, Michael H Tomasson

Open access · bronzeAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. SnoRNAs: The promising targets for anti-tumor therapy.Journal of pharmaceutical analysis · 2024
    Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Epigenetic Regulation of NRF2/KEAP1 by Phytochemicals.Antioxidants (Basel, Switzerland) · 2020
    Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Nitin MahajanDivision of Oncology, Department of Medicine, Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri, USA.
Hua-Jun WuDepartment of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA; and.
Richard L BennettDivision of Hematology and Oncology, Department of Medicine, University of Florida Health Cancer Center, College of Medicine, University of Florida, Gainesville, Florida, USA.
Catalina TrocheDivision of Hematology and Oncology, Department of Medicine, University of Florida Health Cancer Center, College of Medicine, University of Florida, Gainesville, Florida, USA.
Jonathan D LichtDivision of Hematology and Oncology, Department of Medicine, University of Florida Health Cancer Center, College of Medicine, University of Florida, Gainesville, Florida, USA.
Jason D WeberDivision of Oncology, Department of Medicine, Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri, USA.
Leonard B MaggiDivision of Oncology, Department of Medicine, Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri, USA; lmaggi@dom.wustl.edu.
Michael H TomassonDivision of Oncology, Department of Medicine, Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri, USA; tomasson@dom.wustl.edu.
Washington University in St. Louis · USUniversity of Florida Health · USDana-Farber Cancer Institute · USUF Health Cancer Center

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Douglas Robert Spitz · 2000 to 2026
$70.0M
MOLECULAR TARGETS OF TRANSLOCATION T(4;14) IN MULTIPLE MYELOMA PATHOGENESISR01CA175349 · NCI · WASHINGTON UNIVERSITY · PI TOMASSON, MICHAEL H · 2014 to 2018
$1.6M
ROLE OF ACA11, AN ORPHAN SMALL NUCLEOLAR RNA IN RESISTANCE TO CANCER CHEMOTHERAPYR01CA174743 · NCI · WASHINGTON UNIVERSITY · PI MAGGI, LEONARD B, TOMASSON, MICHAEL H · 2013 to 2017
$1.6M
NCI NIH HHS P30 CA091842NCI NIH HHS R01 CA174743NCI NIH HHS R01 CA175349
6 · The paper itself

Abstract

Overexpression of the multiple myeloma set domain (MMSET) Wolf-Hirschhorn syndrome candidate 1 gene, which contains an orphan box H/ACA class small nucleolar RNA, ACA11, in an intron, is associated with several cancer types, including multiple myeloma (MM). ACA11 and MMSET are overexpressed cotranscriptionally as a result of the t(4;14) chromosomal translocation in a subset of patients with MM. RNA sequencing of CD138

Indexed as

AnimalsCell Line, TumorCell ProliferationCells, CulturedFibroblastsGene Expression RegulationHumansMiceMultiple MyelomaNF-E2-Related Factor 2OncogenesOxidative StressReactive Oxygen SpeciesRNA, UntranslatedNFE2L2 protein, humanNfe2l2 protein, mouseNF-E2-Related Factor 2Reactive Oxygen SpeciesRNA, UntranslatedACA11multiple myelomaNRF2ROSsnoRNA

Identifiers

PMID28148777
PMCPMC5240659
OpenAlexW2537405035

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.