Evidence map›Paper›PMID 28148651›Full record

ArticleMolecular biology of the cell2017

An intramolecular interaction within the lipid kinase Fab1 regulates cellular phosphatidylinositol 3,5-bisphosphate lipid levels.

Michael J Lang, Bethany S Strunk, Nadia Azad, Jason L Petersen, Lois S Weisman

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Phosphatidylinositol 3,5-bisphosphate regulates CaTraffic (Copenhagen, Denmark) · 2020
    Article
  8. Article
  9. Control of vacuole membrane homeostasis by a resident PI-3,5-kinase inhibitor.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  10. Article
  11. PI5P and PI(3,5)PCell structure and function · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Michael J LangLife Sciences Institute, University of Michigan, Ann Arbor, MI 48109.
Bethany S StrunkLife Sciences Institute, University of Michigan, Ann Arbor, MI 48109.
Nadia AzadLife Sciences Institute, University of Michigan, Ann Arbor, MI 48109.
Jason L PetersenLife Sciences Institute, University of Michigan, Ann Arbor, MI 48109.
Lois S WeismanLife Sciences Institute, University of Michigan, Ann Arbor, MI 48109 lweisman@umich.edu.
University of Michigan · US

Funding

Regulation of myosin V interaction with cargo-Equipment SupplementR01GM062261 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Lois S Weisman · 2001 to 2026
$5.8M
MOLECULAR BASIS OF ORGANELLE DIVISION AND SEGREGATIONR01GM050403 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WEISMAN, LOIS S · 1994 to 2015
$5.7M
Regulation of Myosin V Interaction with CargoR37GM062261 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WEISMAN, LOIS S · 2009 to 2018
$4.3M
Roles and regulation of PI(3,5)P2 and PI5P in neuronsR01NS064015 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WEISMAN, LOIS S · 2009 to 2018
$3.8M
Lipid phosphatases as dynamic regulators of protein conformationK99GM120511 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI STRUNK, BETHANY S · 2016 to 2017
$178k
NIGMS NIH HHS K99 GM120511NIGMS NIH HHS R01 GM050403NIGMS NIH HHS R37 GM062261NINDS NIH HHS R01 NS064015
6 · The paper itself

Abstract

Phosphorylated phosphoinositide lipids (PPIs) are low-abundance signaling molecules that control signal transduction pathways and are necessary for cellular homeostasis. The PPI phosphatidylinositol (3,5)-bisphosphate (PI(3,5)P

Indexed as

CystineHomeostasisLipidsPhosphatidylinositol 3-KinasesPhosphatidylinositol 4,5-DiphosphatePhosphatidylinositol PhosphatesPhosphatidylinositolsPhosphorylationPhosphotransferases (Alcohol Group Acceptor)Protein DomainsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSignal TransductionCystineFAB1 protein, S cerevisiaeLipidsphosphatidylinositol 3,5-diphosphatePhosphatidylinositol 3-KinasesPhosphatidylinositol 4,5-DiphosphatePhosphatidylinositol PhosphatesPhosphatidylinositolsPhosphotransferases (Alcohol Group Acceptor)Saccharomyces cerevisiae Proteins

Identifiers

PMID28148651
PMCPMC5385934
OpenAlexW2585927953

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.