Evidence map›Paper›PMID 28147345›Full record

ArticleJournal of neurogastroenterology and motility2017

Taste and Smell Disturbances in Patients with Gastroparesis and Gastroesophageal Reflux Disease.

Alisha Kabadi, Mohammed Saadi, Ron Schey, Henry P Parkman

Abstract read
In one paragraph

Article in Journal of neurogastroenterology and motility, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Taste disorder's management: a systematic review.Clinical oral investigations · 2020
    Pooled it
  2. Review
  3. Review
  4. Insight into global burden of gastroesophageal reflux disease: Understanding its reach and impact.World journal of gastrointestinal pharmacology and therapeutics · 2025
    Review
  5. Article
  6. Scoping review: the social and emotional impacts of gastroparesis.Translational gastroenterology and hepatology · 2024
    Article
  7. Alterations in smell or taste in individuals infected with SARS-CoV-2 during periods of Omicron variant dominance.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2023
    Observational
  8. Article
  9. Article
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  14. Article
  15. Olfactory evaluation in obstructive sleep apnoea patients.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alisha KabadiGastroenterology Section, Department of Medicine, Temple University School of Medicine, Philadelphia, PA, USA.
Mohammed SaadiGastroenterology Section, Department of Medicine, Temple University School of Medicine, Philadelphia, PA, USA.
Ron ScheyGastroenterology Section, Department of Medicine, Temple University School of Medicine, Philadelphia, PA, USA.
Henry P ParkmanGastroenterology Section, Department of Medicine, Temple University School of Medicine, Philadelphia, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsPatients with gastroparesis and gastroesophageal reflux disease (GERD) often report decreased enjoyment when eating. Some patients remark that food does not smell or taste the same. To determine if taste and/or smell disturbances are present in patients with gastroparesis and/or GERD and relate these to gastrointestinal symptom severity.

methodsPatients with gastroparesis and/or GERD completed questionnaires evaluating taste and smell (Taste and Smell Survey [TSS]), Patient Assessment of Upper Gastrointestinal Symptom Severity Index (PAGI-SYM), and Demographics. TSS questioned the nature of taste/smell changes and the impact on quality of life. PAGI-SYM was used to calculate Gastroparesis Cardinal Symptom Index (GCSI) and Heartburn and Regurgitation Score (HB/RG).

resultsSeventy-six subjects were enrolled: healthy controls (n = 13), gastroparesis alone (n = 30), GERD alone (n = 10), and both gastroparesis and GERD (n = 23). Taste and smell disturbances were higher in patients with gastroparesis, GERD, and both gastroparesis and GERD compared to healthy controls. Taste and smell abnormalities were significantly correlated (

conclusionsTaste and smell abnormalities are prominent in gastroparesis and GERD patients. Abnormalities in taste and smell are significantly correlated with both gastroparesis and GERD symptom severity. Awareness of this high prevalence of taste and smell dysfunction among patients with gastroparesis and GERD may help to better understand the food intolerances these patients often have.

Indexed as

Gastroesophageal refluxGastroparesisSmellTaste

Identifiers

PMID28147345
PMCPMC5503286

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.