ArticleCell reports2017
Autonomous CaMKII Activity as a Drug Target for Histological and Functional Neuroprotection after Resuscitation from Cardiac Arrest.
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Article in Cell reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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0cells of the map it votes in
47citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
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Who cites it
47 citing papers in PubMed, 65 citations in OpenAlex.
- Multilaboratory, Blinded, Randomized Trial of Five Cerebroprotectants in Ischemic Stroke.Circulation research · 2026Article
- Novel neonatal hypoxic-ischemic model demonstrates glial activation and memory deficits without neuronal loss.Pediatric research · 2026Article
- CaMKII as a Multimodal Signalling Hub in Neural Connectivity and Vulnerability.Molecular neurobiology · 2026Review
- Calcium/calmodulin-dependent protein kinase II inhibition using tatCN19o ameliorates spinal cord ischemia associated with aortic surgery.The Journal of thoracic and cardiovascular surgery · 2026Article
- Microglia interact with dendritic spines and regulate spine numbers after brain injury following resuscitation from a cardiac arrest.Experimental neurology · 2025Article
- The CaMKII D135N mutation blocks kinase activity and reduces GluN2B binding.bioRxiv : the preprint server for biology · 2025Article
- Role of CaMKII/CREB pathway in rapid-antidepressant-like effect: comparison of ketamine with rapastinel.Experimental brain research · 2025Article
- The neuroprotective γ-hydroxybutyrate analog 3-hydroxycyclopent-1-enecarboxylic acid does not directly affect CaMKIIα autophosphorylation at T286 or binding to GluN2B.Molecular pharmacology · 2025Article
- Oxygen/glucose-deprivation causes long-term impairment of synaptic CaMKII movement.bioRxiv : the preprint server for biology · 2025Article
- Synapse-to-Nucleus ERK→CREB Transcriptional Signaling Requires Dendrite-to-Soma CaThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Delayed Fluoxetine Administration Restores Hippocampal Function in a Juvenile Global Cerebral Ischemia Mouse Model in a Sex-Specific Manner.Neural plasticity · 2025Article
- TRPM2 and CaMKII Signaling Drives Excessive GABAergic Synaptic Inhibition Following Ischemia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Studying CaMKII: Tools and standards.Cell reports · 2024Review
- [PI3K/Akt/Erk signaling pathway mediates neuroprotection of CaMKⅡγ and CaMKⅡδ against ischemic reperfusion injury in mice].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024Article
- CaeNeuro · 2024Article
- Astroglial CD38 impairs hippocampal synaptic plasticity after global cerebral ischemia.Frontiers in stroke · 2024Article
- Article
- The GHB analogue HOCPCA improves deficits in cognition and sensorimotor function after MCAO via CaMKIIα.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023Article
- N-Terminomic Changes in Neurons During Excitotoxicity Reveal Proteolytic Events Associated With Synaptic Dysfunctions and Potential Targets for Neuroprotection.Molecular & cellular proteomics : MCP · 2023Article
- Short-term CaMKII inhibition with tatCN19o does not erase pre-formed memory and is neuroprotective in non-rodents.bioRxiv : the preprint server for biology · 2023Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Guiying DengDepartment of Anesthesiology, University of Colorado School of Medicine, Aurora, CO 80045, USA; Neuronal Injury Program, University of Colorado School of Medicine, Aurora, CO 80045, USA.
James E OrfilaDepartment of Anesthesiology, University of Colorado School of Medicine, Aurora, CO 80045, USA; Neuronal Injury Program, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Robert M DietzNeuronal Injury Program, University of Colorado School of Medicine, Aurora, CO 80045, USA; Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Myriam Moreno-GarciaDepartment of Anesthesiology, University of Colorado School of Medicine, Aurora, CO 80045, USA; Neuronal Injury Program, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Krista M RodgersDepartment of Pediatrics, University of Colorado School of Medicine, Aurora, CO 80045, USA; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Steve J CoultrapDepartment of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Nidia QuillinanDepartment of Anesthesiology, University of Colorado School of Medicine, Aurora, CO 80045, USA; Neuronal Injury Program, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Richard J TraystmanDepartment of Anesthesiology, University of Colorado School of Medicine, Aurora, CO 80045, USA; Neuronal Injury Program, University of Colorado School of Medicine, Aurora, CO 80045, USA; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA.
K Ulrich BayerDepartment of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA. Electronic address: ulli.bayer@ucdenver.edu.
Paco S HersonDepartment of Anesthesiology, University of Colorado School of Medicine, Aurora, CO 80045, USA; Neuronal Injury Program, University of Colorado School of Medicine, Aurora, CO 80045, USA; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA. Electronic address: paco.herson@ucdenver.edu.
University of Colorado Denver · US
Funding
Training Program in Perinatal Biology and MedicineT32HD007186 · NICHD · UNIVERSITY OF COLORADO DENVER · PI Paul Joseph Rozance · 1985 to 2026
$6.5MTraining in Basic and Translational Child Health ResearchK12HD068372 · NICHD · UNIVERSITY OF COLORADO DENVER · PI DANIELS, STEPHEN R · 2011 to 2020
$3.7MCaMKII in global cerebral ischemiaR01NS080851 · NINDS · UNIVERSITY OF COLORADO DENVER · PI BAYER, K. ULRICH, HERSON, PACO S · 2013 to 2017
$2.1MTargeting TRPM2 channels to improve synaptic and cognitive function after cerebral ischemiaR01NS092645 · NINDS · UNIVERSITY OF COLORADO DENVER · PI HERSON, PACO S · 2016 to 2020
$1.7MA strategy for pharmacological treatment of global cerebral ischemiaU01NS094261 · NINDS · UNIVERSITY OF COLORADO DENVER · PI BAYER, K. ULRICH · 2017 to 2017
$777kDifferential mechanisms and consequences of Purkinje cell loss in an adult and pediatric model of global cerebral ischemiaK01NS086969 · NINDS · UNIVERSITY OF COLORADO DENVER · PI QUILLINAN, NIDIA · 2015 to 2017
$673kNICHD NIH HHS K12 HD068372NICHD NIH HHS T32 HD007186NINDS NIH HHS K01 NS086969NINDS NIH HHS R01 NS080851NINDS NIH HHS R01 NS092645NINDS NIH HHS U01 NS094261
Abstract
The Ca
Indexed as
AnimalsCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2Cell DeathHeart ArrestHippocampusMaleMiceMice, Inbred C57BLNeuronsNeuroprotectionPhosphorylationCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2CaMKIIcardiac arrestischemiaLTPneuroprotectiontatCN19o
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.