Evidence map›Paper›PMID 28146158›Full record

ArticleMemorias do Instituto Oswaldo Cruz2017

Poor sensitivity of rapid tests for the detection of antibodies to the hepatitis B virus: implications for field studies.

Helena Medina Cruz, Leticia de Paula Scalioni, Vanessa Salete de Paula, Juliana Custódio Miguel, Kycia Maria Rodrigues do Ó, Flavio Augusto Pádua Milagres, Marcelo Santos Cruz, Francisco Inácio Bastos, Priscila Pollo Flores, Erotildes Leal and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Memorias do Instituto Oswaldo Cruz, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Applicability of Oral Fluid and Dried Blood Spot for Hepatitis B Virus Diagnosis.Canadian journal of gastroenterology & hepatology · 2019
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

Helena Medina CruzFundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Hepatites Virais, Rio de Janeiro, RJ, Brasil.
Leticia de Paula ScalioniFundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Hepatites Virais, Rio de Janeiro, RJ, Brasil.
Vanessa Salete de PaulaFundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Desenvolvimento Tecnológico em Virologia, Rio de Janeiro, RJ, Brasil.
Juliana Custódio MiguelFundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Hepatites Virais, Rio de Janeiro, RJ, Brasil.
Kycia Maria Rodrigues do ÓHospital São Lucas, Petrópolis, RJ, Brasil.
Flavio Augusto Pádua MilagresUniversidade Federal do Tocantins, Faculdade de Medicina, Palmas, TO, Brasil.
Marcelo Santos CruzUniversidade Federal do Rio de Janeiro, Instituto de Psiquiatria, Rio de Janeiro, RJ, Brasil.
Francisco Inácio BastosFundação Oswaldo Cruz-Fiocruz, Instituto de Comunicação e Informação Científica e Tecnológica em Saúde, Rio de Janeiro, RJ, Brasil.
Priscila Pollo FloresUniversidade de Brasília, Brasília, DF, Brasil.
Erotildes LealUniversidade Federal do Rio de Janeiro, Campus Macaé, Macaé, RJ, Brasil.
Ana Rita Coimbra Motta-CastroUniversidade Federal do Mato Grosso do Sul, Departamento de Bioquímica e Farmácia, Campo Grande, MS, Brasil.
Lia Laura Lewis-XimenezFundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Hepatites Virais, Rio de Janeiro, RJ, Brasil.
Elisabeth LampeFundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Hepatites Virais, Rio de Janeiro, RJ, Brasil.
Livia Melo VillarFundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Hepatites Virais, Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz · BRUniversidade Federal do Rio de Janeiro · BRHospital São Lucas da PUCRS · BRUniversidade de Brasília · BRUniversidade Federal de Mato Grosso do Sul · BRUniversidade Federal do Tocantins · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapid tests (RTs) can be used as an alternative method for the conventional diagnosis of hepatitis B virus (HBV). This study aims to evaluate antibodies to HBsAg (anti-HBs) and antibodies to HBeAg (anti-HBe) RTs under different Brazilian settings. The following three groups were included: GI: viral hepatitis outpatient services; GII: low resource areas; and GIII: crack users and beauticians. Imuno-rápido anti-HBsAg™ and Imuno-rápido anti-HBeAg™ RTs were evaluated and showed specificities greater than 95% in all groups. The sensitivity values to anti-HBs were 50.38%, 51.05% and 46.73% and the sensitivity values to anti-HBe were 76.99%, 10.34% and 11.76% in the GI, GII and GIII groups, respectively. The assays had a low sensitivity and high specificity, which indicated their use for screening in regions endemic for HBV.

Indexed as

AdultHepatitis BHepatitis B AntibodiesHepatitis B e AntigensHepatitis B Surface AntigensHepatitis B virusHumansMiddle AgedReagent Kits, DiagnosticSensitivity and SpecificityHepatitis B AntibodiesHepatitis B e AntigensHepatitis B Surface AntigensReagent Kits, Diagnostic

Identifiers

PMID28146158
PMCPMC5319371
OpenAlexW2583867222

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.