Evidence map›Paper›PMID 28145752›Full record

ArticleAmerican journal of respiratory and critical care medicine2017

Toward Harnessing Sex Steroid Signaling as a Therapeutic Target in Pulmonary Arterial Hypertension.

Tim Lahm, Andrea L Frump

Abstract readComment
In one paragraph

Article in American journal of respiratory and critical care medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Sex, hormones, and lung health.Physiological reviews · 2026
    Review
  2. Article
  3. Article
  4. Sex and Gender Differences in Lung Disease.Advances in experimental medicine and biology · 2021
    Article
  5. Review
  6. The Y Chromosome Takes the Field to Modify BMPR2 Expression.American journal of respiratory and critical care medicine · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Tim Lahm1 Division of Pulmonary, Critical Care, Occupational and Sleep Medicine Indiana University School of Medicine Indianapolis, Indiana.
Andrea L Frump1 Division of Pulmonary, Critical Care, Occupational and Sleep Medicine Indiana University School of Medicine Indianapolis, Indiana.

Funding

Indiana Clinical and Translational Sciences InstituteTL1TR001107 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$2.0M
Hypoxia-mediated protective estrogen receptor signaling in pulmonary hypertensionI01BX002042 · VA · VA EASTERN COLORADO HEALTH CARE SYSTEM · PI Tim Lahm · 2014 to 2026
–
BLRD VA I01 BX002042NCATS NIH HHS TL1 TR001107
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hypertension, PulmonarySignal TransductionFamilial Primary Pulmonary HypertensionGonadal Steroid HormonesHumansGonadal Steroid Hormones

Identifiers

PMID28145752
PMCPMC5328184

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.