Evidence map›Paper›PMID 28145498›Full record

ArticleScientific reports2017

Unraveling the cytotoxicity and metabolic pathways of binary natural deep eutectic solvent systems.

Yves Paul Mbous, Maan Hayyan, Won Fen Wong, Chung Yeng Looi, Mohd Ali Hashim

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
5.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 163 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Exploitation of ApulianMolecules (Basel, Switzerland) · 2025
    Article
  6. Article
  7. Natural deep eutectic solvents (NaDES): green solvents for pharmaceutical applications and beyond.Green chemistry : an international journal and green chemistry resource : GC · 2025
    Review
  8. Terpene-Based Eutectic Solvent Microdroplets: A Strategy to Combat Antibiotic-ResistantLangmuir : the ACS journal of surfaces and colloids · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yves Paul MbousUniversity of Malaya Centre for Ionic Liquids (UMCiL), University of Malaya, Kuala Lumpur 50603, Malaysia.
Maan HayyanUniversity of Malaya Centre for Ionic Liquids (UMCiL), University of Malaya, Kuala Lumpur 50603, Malaysia.
Won Fen WongDepartment of Medical Microbiology, University of Malaya, Kuala Lumpur 50603, Malaysia.
Chung Yeng LooiDepartment of Pharmacology, University of Malaya, Kuala Lumpur 50603, Malaysia.
Mohd Ali HashimUniversity of Malaya Centre for Ionic Liquids (UMCiL), University of Malaya, Kuala Lumpur 50603, Malaysia.
University of Malaya · MYUniversity Malaya Medical Centre · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, the anticancer potential and cytotoxicity of natural deep eutectic solvents (NADESs) were assessed using HelaS3, PC3, A375, AGS, MCF-7, and WRL-68 hepatic cell lines. NADESs were prepared from choline chloride, fructose, or glucose and compared with an N,N-diethyl ethanolammonium chloride:triethylene glycol DES. The NADESs (98 ≤ EC

Indexed as

AnimalsBiological TransportCell DeathCell Line, TumorCell Membrane PermeabilityCell SurvivalFructoseGlucoseGlycation End Products, AdvancedHydrogen-Ion ConcentrationMetabolic Networks and PathwaysMice, Inbred ICRModels, MolecularOxidation-ReductionReactive Oxygen SpeciesSolventsFructoseGlucoseGlycation End Products, AdvancedReactive Oxygen SpeciesSolvents

Identifiers

PMID28145498
PMCPMC5286504
OpenAlexW2583107873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.