Evidence map›Paper›PMID 28145469›Full record

ArticleScientific reports2017

High-throughput screen detects calcium signaling dysfunction in typical sporadic autism spectrum disorder.

Galina Schmunk, Rachel L Nguyen, David L Ferguson, Kenny Kumar, Ian Parker, J Jay Gargus

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
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  11. Local accumbens in vivo imaging during deep brain stimulation reveals a strategy-dependent amelioration of hedonic feeding.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
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  19. Applying Deep Neural Network Analysis to High-Content Image-Based Assays.SLAS discovery : advancing life sciences R & D · 2019
    Article
  20. Human microbial ecology and the rising new medicine.Annals of translational medicine · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Galina SchmunkDepartment of Physiology and Biophysics, School of Medicine, University of California, Irvine, California, USA.
Rachel L NguyenCenter for Autism Research and Translation, University of California, Irvine, California, USA.
David L FergusonDepartment of Physiology and Biophysics, School of Medicine, University of California, Irvine, California, USA.
Kenny KumarCenter for Autism Research and Translation, University of California, Irvine, California, USA.
Ian ParkerDepartment of Physiology and Biophysics, School of Medicine, University of California, Irvine, California, USA.
J Jay GargusDepartment of Physiology and Biophysics, School of Medicine, University of California, Irvine, California, USA.
Center for Autism and Related Disorders · USUniversity of California, Irvine · US

Funding

University of California Health Participation in the National COVID Cohort Collaborative (N3C)UL1TR001414 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M, VILAIN, ERIC J. · 2015 to 2023
$35.1M
NCATS NIH HHS UL1 TR001414
6 · The paper itself

Abstract

Autism spectrum disorder (ASD) is a heterogeneous group of neurodevelopmental disorders without any defined uniting pathophysiology. Ca

Indexed as

Calcium SignalingTranscriptomeAdenosine TriphosphateAdolescentAdultAutism Spectrum DisorderCalciumCase-Control StudiesChildChild, PreschoolFemaleFibroblastsGene Expression ProfilingHigh-Throughput Screening AssaysHumansMaleAdenosine TriphosphateCalcium

Identifiers

PMID28145469
PMCPMC5286408
OpenAlexW2584925284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.