ArticleScientific reports2017
Sublethal pesticide doses negatively affect survival and the cellular responses in American foulbrood-infected honeybee larvae.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Friend or foe? Concentration of a commensal microbe induces distinct responses in developing honey bees exposed to field-realistic pesticide concentrations.FEMS microbiology ecology · 2025Article
- Honeybee gut bacterial strain improved survival and gut microbiota homeostasis inMicrobiology spectrum · 2024Article
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- Individual and social defenses inFrontiers in physiology · 2023Review
- Bee Stressors from an Immunological Perspective and Strategies to Improve Bee Health.Veterinary sciences · 2022Review
- The threat of pesticide and disease co-exposure to managed and wild bee larvae.International journal for parasitology. Parasites and wildlife · 2022Review
- Endogenous Honeybee Gut Microbiota Metabolize the Pesticide Clothianidin.Microorganisms · 2022Article
- Combined Effects of Pesticides and Electromagnetic-Fields on Honeybees: Multi-Stress Exposure.Insects · 2021Article
- An update of the Worldwide Integrated Assessment (WIA) on systemic insecticides. Part 2: impacts on organisms and ecosystems.Environmental science and pollution research international · 2021Review
- A Pesticide Residues Insight on Honeybees, Bumblebees and Olive Oil after Pesticidal Applications against the Olive Fruit FlyInsects · 2020Article
- Individual and combined impacts of sulfoxaflor andProceedings. Biological sciences · 2020Article
- Cyclic Synthetic Peroxides Inhibit Growth of Entomopathogenic FungusMolecules (Basel, Switzerland) · 2020Article
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- Occurrence of virus, microsporidia, and pesticide residues in three species of stingless bees (Apidae: Meliponini) in the field.Die Naturwissenschaften · 2020Article
- Immunosuppression response to the neonicotinoid insecticide thiacloprid in females and males of the red mason bee Osmia bicornis L.Scientific reports · 2020Article
- American foulbrood in a honeybee colony: spore-symptom relationship and feedbacks.BMC ecology · 2020Article
- Review
- An assessment of acute insecticide toxicity loading (AITL) of chemical pesticides used on agricultural land in the United States.PloS one · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Disclosing interactions between pesticides and bee infections is of most interest to understand challenges that pollinators are facing and to which extent bee health is compromised. Here, we address the individual and combined effect that three different pesticides (dimethoate, clothianidin and fluvalinate) and an American foulbrood (AFB) infection have on mortality and the cellular immune response of honeybee larvae. We demonstrate for the first time a synergistic interaction when larvae are exposed to sublethal doses of dimethoate or clothianidin in combination with Paenibacillus larvae, the causative agent of AFB. A significantly higher mortality than the expected sum of the effects of each individual stressor was observed in co-exposed larvae, which was in parallel with a drastic reduction of the total and differential hemocyte counts. Our results underline that characterizing the cellular response of larvae to individual and combined stressors allows unmasking previously undetected sublethal effects of pesticides in colony health.
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