Evidence map›Paper›PMID 28145440›Full record

ArticleMucosal immunology2017

Tissue-specific differentiation of colonic macrophages requires TGFβ receptor-mediated signaling.

A Schridde, C C Bain, J U Mayer, J Montgomery, E Pollet, B Denecke, S W F Milling, S J Jenkins, M Dalod, S Henri and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Mucosal immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

104 citing papers in PubMed, 150 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
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  12. Gut microbes · 2025
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  13. NADJournal of neuroinflammation · 2025
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  15. Tracing LYVE1bioRxiv : the preprint server for biology · 2025
    Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review

44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 3 countries.

A SchriddeCentre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Scotland, UK.
C C BainCentre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Scotland, UK.
J U MayerCentre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Scotland, UK.
J MontgomeryCentre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Scotland, UK.
E PolletCentre d'Immunologie de Marseille-Luminy, Aix Marseille Université, INSERM, CNRS, Marseille, France.
B DeneckeGenomics Facility IZKF, RWTH Aachen, Aachen, Germany.
S W F MillingCentre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Scotland, UK.
S J Jenkins
M DalodCentre d'Immunologie de Marseille-Luminy, Aix Marseille Université, INSERM, CNRS, Marseille, France.
S HenriCentre d'Immunologie de Marseille-Luminy, Aix Marseille Université, INSERM, CNRS, Marseille, France.
B MalissenCentre d'Immunologie de Marseille-Luminy, Aix Marseille Université, INSERM, CNRS, Marseille, France.
O PabstInstitute of Immunology, Hannover Medical School, Hannover, Germany.
A Mcl MowatCentre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Scotland, UK.
University of Glasgow · GBCentre d’Immunologie de Marseille-Luminy · FRMedizinische Hochschule Hannover · DECentre for Inflammation Research · GBCentre National de la Recherche Scientifique · FRInserm · FRRWTH Aachen University · DEUniversity of Edinburgh · GB

Funding

European Research Council 281225European Research Council 322465Medical Research Council MR/L008076/1Medical Research Council MR/L008289/1Medical Research Council MR/N023625/1Wellcome Trust 094763
6 · The paper itself

Abstract

Intestinal macrophages (mφ) form one of the largest populations of mφ in the body and are vital for the maintenance of gut homeostasis. They have several unique properties and are derived from local differentiation of classical Ly6C

Indexed as

AnimalsAntigens, LyCell DifferentiationCells, CulturedCellular MicroenvironmentColonFemaleGene Expression ProfilingHomeostasisMacrophagesMaleMiceMice, Inbred C57BLMice, KnockoutMonocytesOrgan SpecificityAntigens, LyLy-6C antigen, mouseReceptors, Transforming Growth Factor betaTransforming Growth Factor beta

Identifiers

PMID28145440
PMCPMC5417360
OpenAlexW2585731231

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.