Evidence map›Paper›PMID 28144991›Full record

ArticleDiabetic medicine : a journal of the British Diabetic Association2017

Hypercholesterolaemia screening in Type 1 diabetes: a difference of opinion.

T Candler, O Mahmoud, J Edge, J Hamilton-Shield

Open access · hybridAbstract read
In one paragraph

Article in Diabetic medicine : a journal of the British Diabetic Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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  5. Hypercholesterolaemia screening in Type 1 diabetes: a difference of opinion.Diabetic medicine : a journal of the British Diabetic Association · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

T CandlerBristol Royal Hospital for Children, Upper Maudlin Street, Bristol, UK.
O MahmoudBiomedical Research Unit in Nutrition, Diet and Lifestyle, School of Oral and Dental Sciences, University of Bristol, Bristol, UK.
J EdgeOxford Children's Hospital, Oxford, UK.
J Hamilton-ShieldBristol Royal Hospital for Children, Upper Maudlin Street, Bristol, UK.
Bristol Royal Hospital for Children · GBUniversity of Bristol · GBUniversity Of Bristol Dental Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo assess cholesterol screening of children with Type 1 diabetes by diabetes professionals using a survey of current practice, given that National Institute of Health and Care Excellence guidelines on childhood Type 1 diabetes do not recommend cholesterol screening, yet the National Paediatric Diabetes Audit has an annual cholesterol measure (> 12 years) as a key outcome indicator.

methodsAn online survey was sent to 280 members of the Association of Children's Diabetes Clinicians to assess cholesterol screening practice in children.

resultsA total of 87 diabetes professionals (31%) responded. The results showed that 94% of respondents measured cholesterol, 33% did this annually on all children, and 7% measured fasting cholesterol. A total of 63% used no guidelines to decide treatment or further investigation. The definition of 'high' cholesterol varied from > 4.5 to > 8 mmol/l, with 40% giving no response or specific level. Only 14% of clinicians had started statin therapy in their diabetes clinic in the previous 5 years.

conclusionWhilst the majority of diabetes professionals measured cholesterol in children with Type 1 diabetes, there was marked variability in sampling, in children screened and in action taken if levels were considered abnormal. It is debatable whether cholesterol measures should be undertaken, certainly more than once, and whether cholesterol level should feature as a key outcome in the national audit in future.

Indexed as

Practice Patterns, Physicians'AdolescentAge FactorsChildChild DevelopmentCholesterolDiabetes Mellitus, Type 1Health Care SurveysHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHypercholesterolemiaInternetMass ScreeningPediatriciansPractice Guidelines as TopicSocieties, MedicalCholesterolHydroxymethylglutaryl-CoA Reductase Inhibitors

Identifiers

PMID28144991
PMCPMC5485173
OpenAlexW2554600668

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.