ArticleJournal of materials science. Materials in medicine2017
Biocompatible bacterial cellulose membrane in dural defect repair of rat.
Article in Journal of materials science. Materials in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The trial behind it
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Who cites it
15 citing papers in PubMed.
- Evaluation of Bacterial Cellulose/Alginate-Based Hydrogel and Frog Skin Dressings in Equine Skin Wound Healing.Gels (Basel, Switzerland) · 2025Article
- Article
- Antibacterial and Antibiofilm Potential of Bacterial Cellulose Hydrogel Containing Vancomycin against Multidrug-ResistantBiology · 2024Article
- Melatonin associated with bacterial cellulose-based hydrogel improves healing of skin wounds in diabetic rats.Acta cirurgica brasileira · 2024Article
- Clinical management of dural defects: A review.World journal of clinical cases · 2023Review
- A hydrogel spinal dural patch with potential anti-inflammatory, pain relieving and antibacterial effects.Bioactive materials · 2022Article
- Membrane Technological Pathways and Inherent Structure of Bacterial Cellulose Composites for Drug Delivery.Bioengineering (Basel, Switzerland) · 2021Review
- Bacterial Cellulose Properties Fulfilling Requirements for a Biomaterial of Choice in Reconstructive Surgery and Wound Healing.Frontiers in bioengineering and biotechnology · 2021Review
- Bioapplications of Bacterial Cellulose Polymers Conjugated with Resveratrol for Epithelial Defect Regeneration.Polymers · 2019Article
- Opportunities of Bacterial Cellulose to Treat Epithelial Tissues.Current drug targets · 2019Review
- Cellulose exopolysaccharide from sugarcane molasses as a suitable substrate for 2D and 3D neuron and astrocyte primary cultures.Journal of materials science. Materials in medicine · 2018Article
- Early morphological changes in tissues when replacing abdominal wall defects by bacterial nanocellulose in experimental trials.Journal of materials science. Materials in medicine · 2018Article
- Synthetic biology strategies for improving microbial synthesis of "green" biopolymers.The Journal of biological chemistry · 2018Review
- Article
- Evaluation of Biocompatibility and Healing Properties of Dural Substitutes Produced by Electrospinning Technology.In vivo (Athens, Greece)Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Duraplasty is necessary in nearly 30% of all neurological surgeries. Different tissues and materials have been evaluated in dura mater repair or as dural substitutes in neurosurgery. The aim was to evaluate the biocompatibility of the bacterial cellulose (BC) membranes, produced from sugarcane molasses, for dural defect repair in rats. Forty adults males Wistar rats divided into two groups: a control (ePTFE) and an experimental (BC). Bilateral frontoparietal craniectomy was performed, and a dural defect was created. The arachnoid underlying defect was disrupted with a narrow hook. The animals were observed for 120 days. There were no cases of infection, cerebrospinal fluid fistulae, delayed hemorrhages, behavior disturbances, seizures and palsies. The BC membrane showed to have suitable biocompatibility properties, was not induced immune reaction, nor chronic inflammatory response and absence of neurotoxicity signals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.