Evidence map›Paper›PMID 28144585›Full record

ArticleFrontiers in cellular and infection microbiology2016

Statin Decreases

Wei-Chih Liao, Mei-Zi Huang, Michelle Lily Wang, Chun-Jung Lin, Tzu-Li Lu, Horng-Ren Lo, Yi-Jiun Pan, Yu-Chen Sun, Min-Chuan Kao, Hui-Jing Lim and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. Guideline
  2. Internalization ofAnnals of medicine · 2026
    Review
  3. Inducible antibacterial responses in macrophages.Nature reviews. Immunology · 2025
    Review
  4. Article
  5. Article
  6. Trained Immunity and Trained Tolerance: The Case ofInternational journal of molecular sciences · 2024
    Review
  7. Review
  8. Article
  9. Programmed cell death inFrontiers in cellular and infection microbiology · 2024
    Review
  10. Unveiling the Antibacterial Properties of Statins: AnAdvances in pharmacological and pharmaceutical sciences · 2024
    Article
  11. Virulence · 2023
    Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Simvastatin InhibitsInternational journal of molecular sciences · 2022
    Article
  17. An Overview of Autophagy inFrontiers in cellular and infection microbiology · 2022
    Review
  18. Review
  19. Virulence · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Wei-Chih LiaoGraduate Institute of Clinical Medical Science, China Medical UniversityTaichung, Taiwan; Department of Pulmonary and Critical Care Medicine, China Medical University HospitalTaichung, Taiwan.
Mei-Zi HuangDepartment of Medical Laboratory Science and Biotechnology, China Medical UniversityTaichung, Taiwan; Department of Microbiology and Immunology, Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung UniversityTaoyuan, Taiwan.
Michelle Lily WangGraduate Institute of Basic Medical Science, School of Medicine, China Medical University Taichung, Taiwan.
Chun-Jung LinGraduate Institute of Basic Medical Science, School of Medicine, China Medical UniversityTaichung, Taiwan; Department of Urology, University of Texas Southwestern Medical CenterDallas, TX, USA.
Tzu-Li LuDepartment of Medical Laboratory Science and Biotechnology, China Medical University Taichung, Taiwan.
Horng-Ren LoDepartment of Medical Laboratory Science and Biotechnology, Fooyin University Kaohsiung, Taiwan.
Yi-Jiun PanGraduate Institute of Basic Medical Science, School of Medicine, China Medical University Taichung, Taiwan.
Yu-Chen SunDepartment of Laboratory Medicine, Chang Gung Memorial Hospital Taoyuan, Taiwan.
Min-Chuan KaoDepartment of Microbiology and Immunology, Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University Taoyuan, Taiwan.
Hui-Jing LimDepartment of Microbiology and Immunology, Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University Taoyuan, Taiwan.
Chih-Ho LaiDepartment of Microbiology and Immunology, Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung UniversityTaoyuan, Taiwan; Graduate Institute of Basic Medical Science, School of Medicine, China Medical UniversityTaichung, Taiwan; Department of Nursing, Asia UniversityTaichung, Taiwan; Department of Pediatrics, Molecular Infectious Disease Research Center, Chang Gung Children's Hospital and Chang Gung Memorial HospitalTaoyuan, Taiwan.
China Medical University · TWChang Gung University · TWChang Gung Children's Hospital · TWChang Gung Memorial Hospital · TWFooyin University · TWThe University of Texas Southwestern Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Statins, 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase inhibitors, have been found to provide protective effects against several bacterial infectious diseases. Although the use of statins has been shown to enhance antimicrobial treated

Indexed as

AnimalsAnti-Bacterial AgentsAutophagyBacterial LoadCells, CulturedHelicobacter pyloriHydroxymethylglutaryl-CoA Reductase InhibitorsMacrophagesMiceAnti-Bacterial AgentsHydroxymethylglutaryl-CoA Reductase InhibitorsautophagycholesterolHelicobacter pyloriHMG-CoA reductasestatin

Identifiers

PMID28144585
PMCPMC5239775
OpenAlexW2579353447

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.