ArticleBeilstein journal of nanotechnology2016
A novel electrochemical nanobiosensor for the ultrasensitive and specific detection of femtomolar-level gastric cancer biomarker miRNA-106a.
Article in Beilstein journal of nanotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Rapid and ultra-low detection of cancer biomarker miRNA-133a-3p via AC electrokinetics-integrated capacitive sensing.Mikrochimica acta · 2026Article
- DNA nanotechnology-based strategies for gastric cancer diagnosis and therapy.Materials today. Bio · 2025Review
- Advances in Diagnostic Tools and Therapeutic Approaches for Gliomas: A Comprehensive Review.Sensors (Basel, Switzerland) · 2023Review
- Overview of miR-106a Regulatory Roles: from Cancer to Aging.Bioengineering (Basel, Switzerland) · 2023Review
- Magnetite-Based Biosensors and Molecular Logic Gates: From Magnetite Synthesis to Application.Biosensors · 2023Review
- Evaluation of probe-based ultra-sensitive detection of miRNA using a single-molecule fluorescence imaging method: miR-126 used as the model.Frontiers in bioengineering and biotechnology · 2023Article
- Review
- Diagnosis of Pancreatic Cancer Using miRNA30e Biosensor.Interdisciplinary sciences, computational life sciences · 2022Article
- Application of nanotechnology in the early diagnosis and comprehensive treatment of gastrointestinal cancer.Journal of nanobiotechnology · 2022Review
- Multilayered Mesoporous Composite Nanostructures for Highly Sensitive Label-Free Quantification of Cardiac Troponin-I.Biosensors · 2022Article
- A ratiometric electrochemical DNA-biosensor for detection of miR-141.Mikrochimica acta · 2022Article
- Electrochemiluminescence paper-based screen-printed electrode for HbA1c detection using two-dimensional zirconium metal-organic framework/FeMikrochimica acta · 2021Article
- Electrochemical Biosensors for Detection of MicroRNA as a Cancer Biomarker: Pros and Cons.Biosensors · 2020Review
- Point-of-care biosensors in medicine: a brief overview of our achievements in this field based on the conducted research in EMRI (endocrinology and metabolism research Institute of Tehran University of medical sciences) over the past fourteen years.Journal of diabetes and metabolic disorders · 2020Review
- A review on nanomaterial-based field effect transistor technology for biomarker detection.Mikrochimica acta · 2019Review
- Voltammetric immunosensor for E-cadherin promoter DNA methylation using a FeMikrochimica acta · 2019Article
- Nano-biosensor based on reduced graphene oxide and gold nanoparticles, for detection of phenylketonuria-associated DNA mutation.IET nanobiotechnology · 2018Article
- Voltammetric determination of the Escherichia coli DNA using a screen-printed carbon electrode modified with polyaniline and gold nanoparticles.Mikrochimica acta · 2018Article
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3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gastric cancer (GC) is the second leading cause of cancer-related deaths all over the world. miR-106a is a circulatory oncogenic microRNA (miRNA), which overexpresses in various malignancies, especially in GC. In this study, an ultrasensitive electrochemical nanobiosensor was developed for the detection of miR-106a using a double-specific probe methodology and a gold-magnetic nanocomposite as tracing tag. The successful modification of the electrode and hybridization with the target miRNA were confirmed by electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV) methods. Differential pulse voltammetry (DPV) was used for quantitative evaluation of miR-106a via recording the reduction peak current of gold nanoparticles. The electrochemical signal had a linear relationship with the concentration of the target miRNA ranging from 1 × 10
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