Evidence map›Paper›PMID 28144455›Full record

ArticleIranian Red Crescent medical journal2016

Breastfeeding as a Protective Effect Against Childhood Leukemia and Lymphoma.

Mehran Karimi, Mahmoud Haghighat, Zahra Dialameh, Leila Tahmasbi, Shirin Parand, Marzieh Bardestani

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Iranian Red Crescent medical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07008625 (The Effect of Virtual Reality Application on Anxiety and Milk Quantity in Mothers Who Milk Their Babies by Milking), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07008625 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

The Effect of Virtual Reality Application on Anxiety and Milk Quantity in Mothers Who Milk Their Babies by Milking

TypeinterventionalSponsorMarmara UniversityRan2025 to 2025Enrolled32ConditionsHuman Milk, Breast MilkArmsvirtual reality glasses, routine care
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. The effect of virtual reality on the breastfeeding process: a randomized controlled study.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Trial
  2. Risk of Acute Lymphoblastic Leukemia: Results of a Case-Control Study.Asian Pacific journal of cancer prevention : APJCP · 2019
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mehran KarimiHematology Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran.
Mahmoud HaghighatDepartment of Pediatrics, Shiraz University of Medical Sciences, Shiraz, IR Iran.
Zahra DialamehHematology Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran.
Leila TahmasbiHematology Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran.
Shirin ParandHematology Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran.
Marzieh BardestaniDepartment of Library and Information Science, College of Humanities, Khouzestan Science and research Branch, Islamic Azad University, Ahvaz, IR Iran.
Shiraz University of Medical Sciences · IRIslamic Azad University, Ahvaz Branch · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOver the past several years, breastfeeding has been associated with many benefits as well as protective effects against many diseases. There is limited evidence for the relationship between breastfeeding and the incidence of leukemia.

objectivesIn this study, we evaluate the correlation of childhood leukemia and lymphoma with breastfeeding duration in children in southern Iran. PATIENTS AND

methodsThrough this case control study, we compared 123 patients with leukemia and lymphoma to a control group of 137 healthy children. Statistical analysis was done using the Chi-square test and t-test as well as logistic regression methods. A P-value of less than 0.05 was considered significant.

resultsOur findings showed that breastfeeding duration had no significant difference between cases and controls. However, the rural living percentage in patients with leukemia and lymphoma was higher than in the control group (39.8% versus 14.6% [P < 0.001 and OR = 3.87]) and parents' exposure to chemical materials during the war between Iran and Iraq was higher in sick patients (6.5% versus 0% [OR = 20.2%]).

conclusionsThe current study showed that breastfeeding duration has no protective effect against childhood leukemia and lymphoma. In addition, we suggest that some factors such as living in a rural area, smoking during pregnancy, parents' exposure to chemical materials and low socioeconomic status can increase the incidence rate of childhood leukemia and lymphoma.

Indexed as

BreastfeedingLeukemiaLymphoma

Identifiers

PMID28144455
PMCPMC5253205
OpenAlexW2335954268

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.