Evidence map›Paper›PMID 28144257›Full record

ArticleArchives of medical science : AMS2017

Treatment of denture-related stomatitis improves endothelial function assessed by flow-mediated vascular dilation.

Grzegorz Osmenda, Joanna Maciąg, Grzegorz Wilk, Anna Maciąg, Daniel Nowakowski, Jolanta Loster, Elżbieta Dembowska, Douglas Robertson, Tomasz Guzik, Marta Cześnikiewicz-Guzik

Open access · goldAbstract read
In one paragraph

Article in Archives of medical science : AMS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

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  2. Microorganisms · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Grzegorz OsmendaDepartment of Internal and Agricultural Medicine, Jagiellonian University Collegium Medicum, Krakow, Poland.
Joanna MaciągDepartment of Dental Prophylaxis and Experimental Dentistry, Dental School, Jagiellonian University, Krakow, Poland.
Grzegorz WilkDepartment of Internal and Agricultural Medicine, Jagiellonian University Collegium Medicum, Krakow, Poland.
Anna MaciągZbigniew Żak Voivodeship Dental Clinic, Krakow, Poland.
Daniel NowakowskiDepartment of Dental Prophylaxis and Experimental Dentistry, Dental School, Jagiellonian University, Krakow, Poland.
Jolanta LosterDepartment of Prosthodontics, Dental School, Jagiellonian University, Krakow, Poland.
Elżbieta DembowskaDepartment of Periodontology, Dental School, Pomeranian Medical University, Szczecin, Poland.
Douglas RobertsonOral Sciences Research Group, Glasgow Dental School, School of Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Tomasz GuzikDepartment of Internal and Agricultural Medicine, Jagiellonian University Collegium Medicum, Krakow, Poland; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Marta Cześnikiewicz-GuzikDepartment of Dental Prophylaxis and Experimental Dentistry, Dental School, Jagiellonian University, Krakow, Poland; Oral Sciences Research Group, Glasgow Dental School, School of Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Jagiellonian University · PLUniversity of Glasgow · GBPomeranian Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe presence of oral inflammation has recently been linked with the pathogenesis of cardiovascular diseases. While numerous studies have described links between periodontitis and endothelial dysfunction, little is known about the influence of denture-related stomatitis (DRS) on cardiovascular risk. Therefore, the aim of this study was to determine whether the treatment of DRS can lead to improvement of the clinical measures of vascular dysfunction. MATERIAL AND

methodsThe DRS patients were treated with a local oral antifungal agent for 3 weeks. Blood pressure, flow-mediated dilatation (FMD) and nitroglycerine-mediated vascular dilatation (NMD) were measured during three study visits: before treatment, one day and two months after conclusion of antifungal therapy.

resultsFlow-mediated dilatation measurements showed significant improvement of endothelial function 2 months after treatment (FMD median 5%, 95 CI: 3-8.3 vs. 11%, 95% CI: 8.8-14.4;

conclusionsTreatment of DRS is associated with improvement of endothelial function. Since endothelial dysfunction is known to precede the development of severe cardiovascular disorders such as atherosclerosis and hypertension, patients should be more carefully screened for DRS in general dental practice, and immediate DRS treatment should be advised.

Indexed as

blood pressureCandida albicansdentureendothelial dysfunctionnystatin

Identifiers

PMID28144257
PMCPMC5206372
OpenAlexW2587317904

What OpenQuestion holds

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LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.