Evidence map›Paper›PMID 28144234›Full record

ArticleFrontiers in microbiology2016

Human Catestatin Alters Gut Microbiota Composition in Mice.

Mohammad F Rabbi, Peris M Munyaka, Nour Eissa, Marie-Hélène Metz-Boutigue, Ehsan Khafipour, Jean Eric Ghia

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Pathophysiology of Inflammatory Bowel Disease: Innate Immune System.International journal of molecular sciences · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Alterations of the Mice Gut Microbiome viaFrontiers in microbiology · 2019
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Mohammad F RabbiDepartment of Immunology, University of Manitoba Winnipeg, MB, Canada.
Peris M MunyakaDepartment of Immunology, University of ManitobaWinnipeg, MB, Canada; Department of Animal Sciences, University of ManitobaWinnipeg, MB, Canada.
Nour EissaDepartment of Immunology, University of Manitoba Winnipeg, MB, Canada.
Marie-Hélène Metz-BoutigueBiomaterials and Tissue Engineering, Institut National de la Santé et de la Recherche Médicale Strasbourg, France.
Ehsan KhafipourDepartment of Animal Sciences, University of ManitobaWinnipeg, MB, Canada; Department of Medical Microbiology, University of ManitobaWinnipeg, MB, Canada; The Children's Hospital Research Institute of ManitobaWinnipeg, MB, Canada.
Jean Eric GhiaDepartment of Immunology, University of ManitobaWinnipeg, MB, Canada; The Children's Hospital Research Institute of ManitobaWinnipeg, MB, Canada; Section of Gastroenterology, Department of Internal Medicine, University of ManitobaWinnipeg, MB, Canada; Inflammatory Bowel Disease Clinical and Research Centre, University of ManitobaWinnipeg, MB, Canada.
University of Manitoba · CARegenerative NanoMedicine · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mammalian intestinal tract is heavily colonized with a dense, complex, and diversified microbial populations. In healthy individuals, an array of epithelial antimicrobial agents is secreted in the gut to aid intestinal homeostasis. Enterochromaffin cells (EC) in the intestinal epithelium are a major source of chromogranin A (CgA), which is a pro-hormone and can be cleaved into many bioactive peptides that include catestatin (CST). This study was carried out to evaluate the possible impact of CST on gut microbiota

Indexed as

antimicrobial peptidescatestatin (CST)chromogranin A (CgA)gut microbiotaintestinal homeostasismicrobial dysbiosis

Identifiers

PMID28144234
PMCPMC5239785
OpenAlexW2576594667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.