Evidence map›Paper›PMID 28144131›Full record

Trial reportClinical interventions in aging2017

Cranberry juice concentrate does not significantly decrease the incidence of acquired bacteriuria in female hip fracture patients receiving urine catheter: a double-blind randomized trial.

Anna-Karin Gunnarsson, Lena Gunningberg, Sune Larsson, Kenneth B Jonsson

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical interventions in aging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Cranberries for preventing urinary tract infections.The Cochrane database of systematic reviews · 2023
    Pooled it
  3. Cranberries for preventing urinary tract infections.The Cochrane database of systematic reviews · 2023
    Pooled it
  4. Pooled it
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Catheter-Associated Urinary Tract Infections in Adult Patients.Deutsches Arzteblatt international · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anna-Karin GunnarssonInstitution of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Lena GunningbergInstitution of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden.
Sune LarssonInstitution of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Kenneth B JonssonInstitution of Surgical Sciences, Uppsala University, Uppsala, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUrinary tract infection (UTI) is a common complication among patients with hip fractures. Receiving an indwelling urinary catheter is a risk factor for developing UTIs. Treatment of symptomatic UTIs with antibiotics is expensive and can result in the development of antimicrobial resistance. Cranberries are thought to prevent UTI. There is no previous research on this potential effect in patients with hip fracture who receive urinary catheters.

aimThe aim of this study is to investigate whether intake of cranberry juice concentrate pre-operatively decreases the incidence of postoperative UTIs in hip fracture patients that received a urinary catheter.

designThis study employed a randomized, placebo-controlled double-blind trial.

methodFemale patients, aged 60 years and older, with hip fracture (n=227) were randomized to receive cranberry or placebo capsules daily, from admission, until 5 days postoperatively. Urine cultures were obtained at admission, 5 and 14 days postoperatively. In addition, Euro Qual five Dimensions assessments were performed and patients were screened for UTI symptoms.

resultIn the intention-to-treat analysis, there was no difference between the groups in the proportion of patients with hospital-acquired postoperative positive urine cultures at any time point. When limiting the analysis to patients that ingested at least 80% of the prescribed capsules, 13 of 33 (39%) in the placebo group and 13 of 47 (28%) in the cranberry group (

conclusionCranberry concentrate does not seem to effectively prevent UTIs in female patients with hip fracture and indwelling urinary catheter.

Indexed as

Vaccinium macrocarponAgedAged, 80 and overBacteriuriaCross InfectionDouble-Blind MethodFemaleHip FracturesHumansIncidenceMiddle AgedPhytotherapyPlant ExtractsRisk FactorsUrinary Tract InfectionsPlant Extractselderlyhospitalpreventiverandomized controlled trialurinary tract infectionurine culture

Identifiers

PMID28144131
PMCPMC5245868

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.