Evidence map›Paper›PMID 28144014›Full record

ArticleJournal of microbiology and biotechnology2017

Dendritic Cell-Mediated Mechanisms Triggered by LT-IIa-B

Chang Hoon Lee, George Hajishengallis, Terry D Connell

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of microbiology and biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Cells · 2019
    Article
  2. Modulation of antigen presenting cell functions during chronic HPV infection.Papillomavirus research (Amsterdam, Netherlands) · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Chang Hoon LeeBio & Drug Discovery Division, Center for Drug Discovery Technology, Korea Research Institute of Chemical Technology (KRICT), Daejeon, Republic of Korea.
George HajishengallisDepartment of Microbiology, School of Dental Medicine, The University of Pennsylvania, Philadelphia, PA 19104, USA.
Terry D ConnellDepartment of Microbiology & Immunology and The Witebsky Center for Microbial Pathogenesis and Immunology, The Jacob's School of Medicine and Biomedical Sciences, The University at Buffalo, State University of New York, Buffalo, NY 14214, USA.
Korea Research Institute of Chemical Technology · KR

Funding

Oral Immunity and Adjuvant ReceptorsR01DE017138 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI HAJISHENGALLIS, GEORGIOS · 2006 to 2014
$3.8M
TYPE II Enterotoxins as Mucosal ImmunomodulatorsR01DE013833 · NIDCR · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI CONNELL, TERRY D. · 2001 to 2010
$3.2M
Type II enterotoxins as mucosal immunomodulatorsR56DE013833 · NIDCR · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI CONNELL, TERRY D. · 2011 to 2011
$317k
NIDCR NIH HHS R01 DE013833NIDCR NIH HHS R01 DE017138NIDCR NIH HHS R56 DE013833
6 · The paper itself

Abstract

Mucosal tissues are the initial site through which most pathogens invade. As such, vaccines and adjuvants that modulate mucosal immune functions have emerged as important agents for disease prevention. Herein, we investigated the immunomodulatory mechanisms of the B subunit of

Indexed as

Adjuvants, ImmunologicImmunity, MucosalAdministration, IntranasalAnimalsB7-1 AntigenB7-2 AntigenBacterial ToxinsCD40 AntigensCell MovementChemokinesCytokinesDendritic CellsEnterotoxinsEscherichia coliEscherichia coli ProteinsFemaleAdjuvants, ImmunologicB7-1 AntigenB7-2 AntigenBacterial ToxinsCD40 AntigensChemokinesCytokinesEnterotoxinsEscherichia coli Proteinsheat-labile enterotoxin, E coliReceptors, Cytokinedendritic cellsimmune cell migrationLT-IIa-B5lymph nodemucosal vaccine adjuvant

Identifiers

PMID28144014
PMCPMC5418089
OpenAlexW2611368734

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.