ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017
Targeted Reactivation during Sleep Differentially Affects Negative Memories in Socially Anxious and Healthy Children and Adolescents.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Promoting memory consolidation during sleep: A meta-analysis of targeted memory reactivation.Psychological bulletin · 2020Pooled it
- Anxiety severity in peri-adolescents is associated with greater generalization of negative memories following a period of sleep relative to wake.Journal of child psychology and psychiatry, and allied disciplines · 2025Article
- Targeted memory reactivation during sleep improves emotional memory modulation following imagery rescripting.Translational psychiatry · 2024Article
- Overnight neuronal plasticity and adaptation to emotional distress.Nature reviews. Neuroscience · 2024Review
- Memory reactivation in slow wave sleep enhances relational learning in humans.Communications biology · 2024Article
- Cueing memory reactivation during NREM sleep engenders long-term plasticity in both brain and behaviour.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Rule Abstraction Is Facilitated by Auditory Cuing in REM Sleep.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- The effects of sleep and targeted memory reactivation on the consolidation of relevant and irrelevant information.Frontiers in sleep · 2023Article
- Sleep's role in updating aversive autobiographical memories.Translational psychiatry · 2022Article
- Investigating the effects of sleep and sleep loss on the different stages of episodic emotional memory: A narrative review and guide to the future.Frontiers in behavioral neuroscience · 2022Review
- Article
- Exposure to relaxing words during sleep promotes slow-wave sleep and subjective sleep quality.Sleep · 2021Article
- Targeted memory reactivation in REM but not SWS selectively reduces arousal responses.Communications biology · 2021Article
- Memory and Sleep: How Sleep Cognition Can Change the Waking Mind for the Better.Annual review of psychology · 2021Article
- Effects of targeted memory reactivation during sleep at home depend on sleep disturbances and habituation.NPJ science of learning · 2019Article
- (Re)Conceptualizing Sleep Among Children with Anxiety Disorders: Where to Next?Clinical child and family psychology review · 2018Review
- Acquiring New Factual Information: Effect of Prior Knowledge.Frontiers in psychology · 2018Article
- Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cognitive models propose a negative memory bias as one key factor contributing to the emergence and maintenance of social anxiety disorder (SAD). The long-term consolidation of memories relies on memory reactivations during sleep. We investigated in SAD patients and healthy controls the role of memory reactivations during sleep in the long-term consolidation of positive and negative information. Socially anxious and healthy children and adolescents learnt associations between pictures showing ambiguous situations and positive or negative words defining the situations' outcome. Half of the words were re-presented during postlearning sleep (i.e., they were cued). Recall of picture-word associations and subjective ratings of pleasantness and arousal in response to the pictures was tested for cued and uncued stimuli. In the morning after cueing, cueing facilitated retention of positive and negative memories equally well in SAD patients and healthy controls. One week later, cueing led to reduced ratings of pleasantness of negative information in SAD but not in healthy controls. Coincidental to these findings was more pronounced EEG theta activity over frontal, temporal and parietal regions in response to negative stimuli in SAD patients. Our findings suggest that the preferential abstraction of negative emotional information during sleep might represent one factor underlying the negative memory bias in SAD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.