ReviewAmerican journal of physiology. Endocrinology and metabolism2017
Timing of meals: when is as critical as what and how much.
Review in American journal of physiology. Endocrinology and metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05163964 (Chronotype, Chrononutrition and Glucose Tolerance Among Prediabetic Individuals), which is not on this map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Chronotype, Chrononutrition and Glucose Tolerance Among Prediabetic Individuals: Chrono-DM TM
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of time-restricted feeding on body weight and metabolism. A systematic review and meta-analysis.Reviews in endocrine & metabolic disorders · 2020Pooled it
- Effect of changes in children's bedtime and sleep period on targeted eating behaviors and timing of caloric intake.Eating behaviors · 2022Trial
- Trial
- Gut-brain axis in health and brain disease.Chinese medical journal · 2026Review
- Review
- Chronotype and associations with dietary intake, meal timing, body composition, and metabolic biomarkers.Frontiers in nutrition · 2026Article
- Segment-Specific Functional Responses of Swine Intestine to Time-Restricted Feeding Regime.Animals : an open access journal from MDPI · 2025Article
- Endocrine regulation of circadian rhythms.Npj biological timing and sleep · 2025Review
- The associations between evening eating and quality of energy and macronutrients and obesity: the National Health and Nutrition Examination Survey (NHANES), 2003-2016.Nutrition journal · 2025Article
- Feasibility of an At-Home Experimental Circadian Misalignment Induction for Adolescents.Clocks & sleep · 2025Article
- The effects of meal patterns on liver steatosis, fibrosis, and biochemical factors in patients with nonalcoholic fatty liver disease: a randomized controlled clinical trial.Journal of diabetes and metabolic disorders · 2024Article
- Association of Nightly Fasting, Meal Frequency, and Skipping Meals with Metabolic Syndrome among Kuwaiti Adults.Nutrients · 2024Article
- Association between CLOCK gene polymorphisms with circadian rhythm, chrononutrition, dietary intake, and metabolic parameters in adolescents.Frontiers in public health · 2024Article
- Sleep insufficiency, circadian rhythms, and metabolomics: the connection between metabolic and sleep disorders.Sleep & breathing = Schlaf & Atmung · 2023Review
- Timing of energy intake and BMI in children: differential impacts by age and sex.The British journal of nutrition · 2023Article
- Prolonged fasting times reap greater geroprotective effects when combined with caloric restriction in adult female mice.Cell metabolism · 2023Article
- Article
- Behavior and physiology in femaleFrontiers in endocrinology · 2023Article
- Chronotype Differences in Body Composition, Dietary Intake and Eating Behavior Outcomes: A Scoping Systematic Review.Advances in nutrition (Bethesda, Md.) · 2022Article
- Chronotype, chrononutrition and glucose tolerance among prediabetic individuals: research protocol for a prospective longitudinal study Chrono-DM™.BMC primary care · 2022Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Over the past decade, a large body of literature has demonstrated that disruptions of the endogenous circadian clock, whether environmental or genetic, lead to metabolic dysfunctions that are associated with obesity, diabetes, and other metabolic disorders. The phrase, "It is not only what you eat and how much you eat, but also when you eat" sends a simple message about circadian timing and body weight regulation. Communicating this message to clinicians and patients, while also elucidating the neuroendocrine, molecular, and genetic mechanisms underlying this phrase is essential to embrace the growing knowledge of the circadian impact on metabolism as a part of healthy life style as well as to incorporate it into clinical practice for improvement of overall human health. In this review, we discuss findings from animal models, as well as epidemiological and clinical studies in humans, which collectively promote the awareness of the role of circadian clock in metabolic functions and dysfunctions.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.