Evidence map›Paper›PMID 28143672›Full record

ArticleAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2017

Echocardiographic Measures and Estimated GFR Decline Among African Americans: The Jackson Heart Study.

Leila R Zelnick, Ronit Katz, Bessie A Young, Adolfo Correa, Bryan R Kestenbaum, Ian H de Boer, Nisha Bansal

Abstract read
In one paragraph

Article in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Association of Left Atrial Function With Incident Chronic Kidney Disease in Older Adults.Mayo Clinic proceedings. Innovations, quality & outcomes · 2024
    Article
  2. Article
  3. Article
  4. Cardiac Structure and Function and Subsequent Kidney Disease Progression in Adults With CKD: The Chronic Renal Insufficiency Cohort (CRIC) Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2023
    Observational
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Kidney Appreciates Stable Blood Pressure.American journal of hypertension · 2018
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Leila R ZelnickKidney Research Institute, University of Washington, Seattle, WA; Division of Nephrology, University of Washington, Seattle, WA. Electronic address: lzelnick@uw.edu.
Ronit KatzKidney Research Institute, University of Washington, Seattle, WA; Division of Nephrology, University of Washington, Seattle, WA.
Bessie A YoungKidney Research Institute, University of Washington, Seattle, WA; Division of Nephrology, University of Washington, Seattle, WA; Center of Innovation, Veterans Affairs Puget Sound Health Care System, Seattle, WA; Hospital and Specialty Care, Veterans Affairs Puget Sound Health Care System, Seattle, WA.
Adolfo CorreaDepartment of Medicine, University of Mississippi Medical Center, Jackson, MS.
Bryan R KestenbaumKidney Research Institute, University of Washington, Seattle, WA; Division of Nephrology, University of Washington, Seattle, WA.
Ian H de BoerKidney Research Institute, University of Washington, Seattle, WA; Division of Nephrology, University of Washington, Seattle, WA.
Nisha BansalKidney Research Institute, University of Washington, Seattle, WA; Division of Nephrology, University of Washington, Seattle, WA.
University of Washington · USUniversity of Mississippi Medical Center · US

Funding

Blood Pressure in Advanced Chronic Kidney DiseaseK23DK088865 · NIDDK · UNIVERSITY OF WASHINGTON · PI BANSAL, NISHA · 2010 to 2014
$848k
CKD-Targeted Analyses of the Jackson Heart StudyR01DK102134 · NIDDK · UNIVERSITY OF WASHINGTON · PI YOUNG, BESSIE ANN · 2013 to 2015
$829k
NHLBI NIH HHS HHSN268201300046CNHLBI NIH HHS HHSN268201300047CNIDDK NIH HHS K23 DK088865NIDDK NIH HHS R01 DK102134
6 · The paper itself

Abstract

backgroundCardiac structural abnormalities, common in African Americans, are associated with adverse clinical outcomes. Associations between echocardiography-measured subclinical heart failure and kidney function decline are unknown and may identify novel risk factors for kidney disease in this population. STUDY

designProspective cohort study. SETTING &

participants2,418 Jackson Heart Study participants with baseline echocardiograms and longitudinal measures of estimated glomerular filtration rate (eGFR) calculated from the CKD-EPI creatinine equation. 2,219 participants had baseline eGFRs≥60mL/min/1.73m PREDICTORS: Left ventricular mass (LVM) and ejection fraction (LVEF) and pulmonary artery systolic pressure (PASP) quantified from baseline echocardiograms. OUTCOMES: Primary outcome was >30% eGFR decline or progression to end-stage renal disease (ESRD; need for dialysis therapy) over a mean of 8 years. Secondary outcome, eGFR<60mL/min/1.73m MEASUREMENTS: Logistic regression models, adjusted for demographics, physical characteristics, comorbid conditions, and medication use.

resultsMean age was 52.2±11.9 (SD) years, 37% of participants were men; mean baseline eGFR was 87.3±17.3mL/min/1.73m LIMITATIONS: No midstudy creatinine measurement at examination 2.

conclusionsGreater LVM was significantly associated with eGFR decline > 30% or ESRD among African Americans in a community-based cohort. Treating and reversing elevated LVM may reduce the burden and progression of kidney disease in this high-risk population.

Indexed as

Black or African AmericanEchocardiographyGlomerular Filtration RateDisease ProgressionFemaleHeart FailureHumansKidney Failure, ChronicMaleMiddle AgedProspective StudiesAfrican AmericansechocardiogrameGFR declineejection fraction (LVEF)end-stage renal disease (ESRD)estimated glomerular filtration rate (eGFR)incident ESRDkidney disease progressionkidney function declineleft ventricular mass (LVM)pulmonary artery systolic pressure (PASP)Subclinical heart failure

Identifiers

PMID28143672
PMCPMC5848095
OpenAlexW2580692884

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.