Evidence map›Paper›PMID 28143670›Full record

Observational studyAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2017

Maternal and Fetal Folate, Vitamin B

Kozeta Miliku, Anne Mesu, Oscar H Franco, Albert Hofman, Eric A P Steegers, Vincent W V Jaddoe

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Impact of Maternal Folic Acid Supplementation on Descendants' Kidney in Adulthood.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2023
    Pooled it
  4. Pooled it
  5. Review
  6. Article
  7. Nonlinear Relationship Between Maternal and Cord Blood Vitamin BInternational journal of women's health · 2023
    Article
  8. Review
  9. Review
  10. The First Thousand Days: Kidney Health and Beyond.Healthcare (Basel, Switzerland) · 2021
    Review
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kozeta MilikuThe Generation R Study Group, Erasmus University Medical Center, Rotterdam, the Netherlands; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands; Department of Pediatrics, Erasmus University Medical Center, Rotterdam, the Netherlands.
Anne MesuThe Generation R Study Group, Erasmus University Medical Center, Rotterdam, the Netherlands.
Oscar H FrancoDepartment of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.
Albert HofmanDepartment of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.
Eric A P SteegersDepartment of Obstetrics and Gynaecology, Erasmus University Medical Center, Rotterdam, the Netherlands.
Vincent W V JaddoeThe Generation R Study Group, Erasmus University Medical Center, Rotterdam, the Netherlands; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands; Department of Pediatrics, Erasmus University Medical Center, Rotterdam, the Netherlands. Electronic address: v.jaddoe@erasmusmc.nl.
Erasmus MC · NL

Funding

European Research Council 648916
6 · The paper itself

Abstract

backgroundFolate, vitamin B STUDY

designPopulation-based prospective cohort study from fetal life onward. SETTINGS &

participantsThis study was performed among 4,226 pregnant women and their children. PREDICTORS: Folate, vitamin B OUTCOMES & MEASUREMENTS: At the median age of 6.0 (IQR, 5.9-6.3) years, we measured combined kidney volume with ultrasound, estimated glomerular filtration rate based on creatinine (eGFR

resultsWe observed that higher maternal folate concentrations were associated with larger childhood combined kidney volume, whereas higher maternal vitamin B LIMITATIONS: Observational study, so causality cannot be established.

conclusionsOur findings suggest that folate, vitamin B

Indexed as

Kidney Function TestsAlbuminuriaChildChild, PreschoolCohort StudiesFemaleFetal BloodFolic AcidFollow-Up StudiesGlomerular Filtration RateHomocysteineHumansInfantInfant, NewbornMaleMaternal-Fetal ExchangeFolic AcidHomocysteineVitamin B 12epidemiologyestimated glomerular filtration rate (eGFR)fetal nutritional exposureFolategestationhomocysteinekidney developmentkidney functionkidney volumematernal nutritionmethyl donorsmodifiable risk factornephrogenesispediatricspregnancyvitamin B(12)

Identifiers

PMID28143670
PMCPMC5408932
OpenAlexW2581325782

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.