ArticleMicrobiome2017
Gut symbiont enhances insecticide resistance in a significant pest, the oriental fruit fly Bactrocera dorsalis (Hendel).
Article in Microbiome, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 164 papers.
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Who cites it
164 citing papers in PubMed, 416 citations in OpenAlex.
- Comparative analyses of the Serratia marcescens complex reveal variations in their pathogenicity against a fruit pest.Pest management science · 2026Article
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- Structure of the Gut and Ovary, with Associated Microbiota Across Life Stages in the Striped Stem BorerInsects · 2026Article
- Review
- Symbiont-mediated mechanisms of insecticide resistance in insects.Journal of insect science (Online) · 2026Review
- Composition and Diversity Characteristics of Gut Microbiota during the Development ofEcology and evolution · 2026Article
- Evolution, multifunctionality, and agricultural potential of insect microbiomes and the holobiont concept.The ISME journal · 2026Review
- Aedes albopictus gut symbiotic bacterium Bacillus cereus improves its deltamethrin resistance.Parasites & vectors · 2026Article
- The intestinalMicrobiology spectrum · 2026Article
- Evolutionary dynamics of type VI secretion systems in fruit fly-associatedFrontiers in microbiology · 2026Article
- Cultivation substrates alter plant metabolic profiles with concomitant impacts on herbivore performance.Frontiers in microbiology · 2026Article
- Review
- Comparative Analysis of Symbiotic Bacterial Diversity and Sublethal Effects of Nitenpyram Against Two Different Cotton Aphids.Biology · 2025Article
- Effects of X-Ray Irradiation on the Biological Parameters, Gut Microbiota, and Gene Expression ofEvolutionary applications · 2025Article
- Assessing gut microbiota diversity and functional potential in resistant and susceptible strains of the mediterranean fruit fly.Scientific reports · 2025Article
- Mechanisms and Genetic Drivers of Resistance of Insect Pests to Insecticides and Approaches to Its Control.Toxics · 2025Review
- Gut bacteria contribute to fenvalerate resistance in the tomato leafminer, Tuta absoluta.Scientific reports · 2025Article
- Gut symbiotic bacteria enhance reproduction in Spodoptera frugiperda (J.E. Smith) by regulating juvenile hormone III and 20-hydroxyecdysone pathways.Microbiome · 2025Article
- Article
- Bacterial communities inHeliyon · 2025Article
104 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSymbiotic bacteria affect insect physiology and ecology. They may also mediate insecticide resistance within their hosts and thereby impact pest and vector control practices. Here, we document a novel mechanism of insecticide resistance in which a gut symbiont of the tephritid pest fruit fly Bactrocera dorsalis enhances resistance to the organophosphate insecticide trichlorphon.
resultsWe demonstrated that the gut symbiont Citrobacter sp. (CF-BD) plays a key role in the degradation of trichlorphon. Based on a comparative genomics analysis with other Citrobacter species, phosphatase hydrolase genes were identified in CF-BD. These CF-BD genes had higher expression when trichlorphon was present. Bactrocera dorsalis inoculated with isolated CF-BD obtained higher trichlorphon resistance, while antibiotic-treated flies were less resistant confirming the key role of CF-BD in insecticide resistance.
conclusionsOur findings suggest that symbiont-mediated insecticide resistance can readily develop in B. dorsalis and may represent a more widely relevant insecticide resistance mechanism than previously recognized.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.