ArticleBMC pediatrics2017
Pathogenic bacteria distributions and drug resistance analysis in 96 cases of neonatal sepsis.
Article in BMC pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 37 citations in OpenAlex.
- Identification of bacterial pathogens and antimicrobial susceptibility of early-onset sepsis (EOS) among neonates in Palestinian hospitals: a retrospective observational study.BMC pediatrics · 2025Observational
- Early onset neonatal bloodstream infections in South African hospitals.BMC infectious diseases · 2025Article
- Increase in methicillin-resistant Staphylococcus spp. colonization among pregnant individuals during COVID-19 pandemic.Scientific reports · 2024Article
- Article
- Bacteriological Profile and Antibiotic Susceptibility Pattern of Neonatal Septicemia and Associated Factors of ICU Hospitalization Days.Infection and drug resistance · 2022Article
- Bacterial Pathogens and Evaluation of a Cut-Off for Defining Early and Late Neonatal Infection.Antibiotics (Basel, Switzerland) · 2021Article
- Untargeted and Targeted Metabolomic Profiling of Preterm Newborns with EarlyOnset Sepsis: A Case-Control Study.Metabolites · 2021Article
- Identification of key genes associated with sepsis patients infected by staphylococcus aureus through weighted gene co-expression network analysis.American journal of translational research · 2021Article
- Detailed nursing intervention on neonatal septicemia can improve the clinical symptoms of children and reduce the inflammatory reaction.American journal of translational research · 2021Article
- Changing trends in the bacteriological profiles and antibiotic susceptibility in neonatal sepsis at a tertiary children's hospital of China.Translational pediatrics · 2020Article
- Observational
- Incidence, Bacterial Profiles, And Antimicrobial Resistance Of Culture-Proven Neonatal Sepsis In South China.Infection and drug resistance · 2019Article
- Higher intake of coagulase-negative staphylococci from maternal milk promotes gut colonization with mecA-negative Staphylococcus epidermidis in preterm neonates.Journal of perinatology : official journal of the California Perinatal Association · 2018Observational
- Activation of the Akt/mTOR signaling pathway: A potential response to long-term neuronal loss in the hippocampus after sepsis.Neural regeneration research · 2017Article
- Clinical analysis of distribution and drug resistance of pathogenic bacteria in blood culture of Dalian Municipal Central Hospital from 2015 to 2019.Pakistan journal of medical sciencesArticle
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to summarize common pathogens and associated drug resistance in neonatal sepsis (NS).
methodsBlood culture and drug sensitivity results from 96 NS cases treated from January 2010 to August 2014 were retrospectively analyzed.
resultsA total of 97 pathogenic bacteria were detected from these 96 NS cases; Gram-positive cocci accounted for 76.3% of the cases, among which 70.1% involved coagulase-negative staphylococcus (CONS), whereas Gram-negative bacilli and fungi accounted for 19.6% and fungi 4.1% of cases, respectively. Gram-positive cocci exhibited a higher penicillin resistance rate and full vancomycin sensitivity, whereas Gram-negative bacilli exhibited a higher cephalosporin resistance rate, low meropenem resistance rate (6.7%), and no resistance to amikacin.
conclusionsThe main causative pathogens of NS in our hospital were Gram-positive cocci, among which coagulase-negative Staphylococcus spp such as S. epidermidis and S. haemolyticus were the main conditional pathogens; among Gram-negative pathogens, Klebsiella pneumoniae were most frequently isolated and showed widespread resistance to penicillins and cephalosporins.
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