Evidence map›Paper›PMID 28143410›Full record

ArticleBMC cardiovascular disorders2017

Correlations of serum cystatin C and glomerular filtration rate with vascular lesions and severity in acute coronary syndrome.

Jinjin Zhang, Xianhao Wu, Peizhen Gao, Pingping Yan

Open access · goldAbstract readComparative StudyEvaluation Study
In one paragraph

Article in BMC cardiovascular disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Analysis of risk factors for different subtypes of acute coronary syndrome.The Journal of international medical research · 2021
    Article
  5. Article
  6. Article
  7. Article
  8. Cystatin C as a Biomarker for Identifying High-Risk Patients with Acute Coronary Syndrome: An Observational Study.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jinjin ZhangDepartment of Cardiology, North Huashan Hospital of Fudan University, Shanghai, 201907, People's Republic of China.
Xianhao WuDepartment of Cardiology, Tongren Hospital, Shanghai, 200050, People's Republic of China.
Peizhen GaoDepartment of Beixinjing Community Health Center, Shanghai, 200335, People's Republic of China.
Pingping YanDepartment of Cardiology, North Huashan Hospital of Fudan University, Shanghai, 201907, People's Republic of China. pingpingyandoc@163.com.
Huashan Hospital · CNTongren Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to evaluate the predictive value of cystatin C (CysC) and estimated glomerular filtration rate (eGFR) regarding vascular lesions and their severity in patients with acute coronary syndrome (ACS).

methodsAccording to the results of coronary angiography, 195 ACS patients were divided into a single-vascular-lesion group (91 cases), a dual-vascular-lesion group (67 cases), and a multiple-vascular-lesion group (37 cases) to assess the severity of coronary artery disease according to Gensini scores and to analyze the correlations of CysC and eGFR level with vascular lesions and severity in ACS patients.

resultsIntergroup comparisons of univariate and multivariate regression analyses showed that CysC was positively correlated with vascular lesions (P < 0.05), but eGFR showed no correlation. Regarding the severity of vascular lesions, CysC was positively correlated with Gensini score (Pearson's correlation coefficient r = 0.1811, P < 0.05), but eGFR was not correlated (P > 0.05).

conclusionsSerum CysC levels could reflect the severity of vascular lesions in ACS patients, and a high CysC level had predictive value regarding the severity of vascular lesions in ACS.

Indexed as

Glomerular Filtration RateAcute Coronary SyndromeAgedBiomarkersChi-Square DistributionCoronary AngiographyCoronary Artery DiseaseCoronary StenosisCystatin CFemaleHumansKidneyLinear ModelsLogistic ModelsMaleMiddle AgedBiomarkersCST3 protein, humanCystatin CAcute coronary syndromeCorrelation studyGlomerular filtration rateSerum cystatin C

Identifiers

PMID28143410
PMCPMC5282728
OpenAlexW2584943498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.