Evidence map›Paper›PMID 28142201›Full record

ArticleClinical and experimental immunology2017

Lymph node and circulating T cell characteristics are strongly correlated in end-stage renal disease patients, but highly differentiated T cells reside within the circulation.

B Dedeoglu, A E de Weerd, L Huang, A W Langerak, F J Dor, M Klepper, W Verschoor, D Reijerkerk, C C Baan, N H R Litjens and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Clinical and experimental immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Co-inhibitory profile and cytotoxicity of CD57Clinical and experimental immunology · 2018
    Trial
  3. Characteristics of T cell premature senescence in maintenance hemodialysis patients.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Article
  4. Review
  5. Article
  6. Early cytomegalovirus DNAemia and antiviral dose adjustment in high vs intermediate risk kidney transplant recipients.Transplant infectious disease : an official journal of the Transplantation Society · 2021
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Human immunology studies using organ donors: Impact of clinical variations on immune parameters in tissues and circulation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2018
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

B DedeogluDepartment of Internal Medicine, section Nephrology and Transplantation, Erasmus University Medical Center, Rotterdam, the Netherlands.
A E de WeerdDepartment of Internal Medicine, section Nephrology and Transplantation, Erasmus University Medical Center, Rotterdam, the Netherlands.
L HuangDepartment of Internal Medicine, section Nephrology and Transplantation, Erasmus University Medical Center, Rotterdam, the Netherlands.
A W LangerakDepartment of Immunology, Erasmus University Medical Center, Rotterdam, the Netherlands.
F J DorDepartment of Surgery, Erasmus University Medical Center, Rotterdam, the Netherlands.
M KlepperDepartment of Internal Medicine, section Nephrology and Transplantation, Erasmus University Medical Center, Rotterdam, the Netherlands.
W VerschoorDepartment of Internal Medicine, section Nephrology and Transplantation, Erasmus University Medical Center, Rotterdam, the Netherlands.
D ReijerkerkDepartment of Internal Medicine, section Nephrology and Transplantation, Erasmus University Medical Center, Rotterdam, the Netherlands.
C C BaanDepartment of Internal Medicine, section Nephrology and Transplantation, Erasmus University Medical Center, Rotterdam, the Netherlands.
N H R LitjensDepartment of Internal Medicine, section Nephrology and Transplantation, Erasmus University Medical Center, Rotterdam, the Netherlands.
M G H BetjesDepartment of Internal Medicine, section Nephrology and Transplantation, Erasmus University Medical Center, Rotterdam, the Netherlands.
Erasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ageing is associated with changes in the peripheral T cell immune system, which can be influenced significantly by latent cytomegalovirus (CMV) infection. To what extent changes in circulating T cell populations correlate with T cell composition of the lymph node (LN) is unclear, but is crucial for a comprehensive understanding of the T cell system. T cells from peripheral blood (PB) and LN of end-stage renal disease patients were analysed for frequency of recent thymic emigrants using CD31 expression and T cell receptor excision circle content, relative telomere length and expression of differentiation markers. Compared with PB, LN contained relatively more CD4

Indexed as

AgedAgingAntigens, Differentiation, T-LymphocyteCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell DifferentiationCytomegalovirus InfectionsFemaleHumansImmunologic MemoryKidney Failure, ChronicLymph NodesLymphocyte ActivationLymphocyte CountMaleMiddle AgedAntigens, Differentiation, T-LymphocytePlatelet Endothelial Cell Adhesion Molecule-1ageingend-stage renal diseaselymph nodeperipheral bloodT cells

Identifiers

PMID28142201
PMCPMC5383449
OpenAlexW2583979041

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.