Evidence map›Paper›PMID 28140833›Full record

ArticleJournal of toxicology and environmental health. Part A2017

Nanoparticles-induced apoptosis of human airway epithelium is mediated by proNGF/p75

Sreeparna Chakraborty, Vincent Castranova, Miriam K Perez, Giovanni Piedimonte

Open access · greenAbstract read
In one paragraph

Article in Journal of toxicology and environmental health. Part A, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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  12. Engineered nanomaterial-induced lysosomal membrane permeabilization and anti-cathepsin agents.Journal of toxicology and environmental health. Part B, Critical reviews · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sreeparna Chakrabortya Department of Pediatrics , West Virginia University School of Medicine , Morgantown , West Virginia , USA.
Vincent Castranovab Department of Pharmaceutical Science , West Virginia University School of Pharmacy , Morgantown , West Virginia , USA.
Miriam K Perezc Pediatric Institute and Children's Hospital, Cleveland Clinic Foundation , Cleveland , Ohio , USA.
Giovanni Piedimontec Pediatric Institute and Children's Hospital, Cleveland Clinic Foundation , Cleveland , Ohio , USA.
Cleveland Clinic · USWest Virginia University · US

Funding

THE ROLE OF HEF1 PROTEIN IN INVASION OF METASTATIC BREAST CANCERP20RR016440 · NCRR · WEST VIRGINIA UNIVERSITY · PI CUFF, CHRISTOPHER F · 2001 to 2010
$22.8M
NEUROGENIC INFLAMMATORY RESPONSE TO RSVR01HL061007 · NHLBI · WEST VIRGINIA UNIVERSITY · PI PIEDIMONTE, GIOVANNI · 1999 to 2022
$7.2M
BECTON-DICKINSON FACSARIA FLOW CYTOMETER: SARCOPENIAS10RR020866 · NCRR · WEST VIRGINIA UNIVERSITY · PI CUFF, CHRISTOPHER F · 2006 to 2006
$425k
NCRR NIH HHS P20 RR016440NCRR NIH HHS S10 RR020866NHLBI NIH HHS R01 HL061007
6 · The paper itself

Abstract

Environmental and occupational exposures to respirable ultrafine fractions of particulate matter (PM) have been implicated in the initiation and exacerbation of lung diseases. However, the precise mechanisms underlying production of cell damage and death attributed to nanoparticles (NP) on human airway epithelium are not fully understood. This study examined the role of neurotrophic pathways in NP-induced airway toxicity. Size and agglomeration of TiO

Indexed as

ApoptosisEpithelial CellsGene Expression RegulationHumansMetal NanoparticlesNerve Growth FactorsParticle SizeParticulate MatterReceptors, Nerve Growth FactorRespiratory SystemTitaniumNerve Growth FactorsParticulate MatterReceptors, Nerve Growth FactorTitaniumtitanium dioxide

Identifiers

PMID28140833
PMCPMC5597962
OpenAlexW2584255762

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.