Evidence map›Paper›PMID 28140785›Full record

ArticleCognitive neuroscience2017

A defense of using resting-state fMRI as null data for estimating false positive rates.

Thomas E Nichols, Anders Eklund, Hans Knutsson

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cognitive neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Insula Sensitivity to Unfairness in Alcohol Use Disorder.Alcohol and alcoholism (Oxford, Oxfordshire) · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Thomas E Nicholsa Department of Statistics , University of Warwick , Coventry , UK.
Anders Eklundc Division of Medical Informatics, Department of Biomedical Engineering , Linköping University , Linköping , Sweden.
Hans Knutssonc Division of Medical Informatics, Department of Biomedical Engineering , Linköping University , Linköping , Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A recent Editorial in Cognitive Neuroscience reconsiders the findings of our work on the accuracy of false positive rate control with cluster inference in functional magnetic resonance imaging (fMRI), in particular criticizing our use of resting-state fMRI as a source for null data in the evaluation of task fMRI methods. We defend this use of resting fMRI data, as while there is much structure in this data, we argue it is representative of task data noise and task analysis software should be able to accommodate this noise. We also discuss a potential problem with Slotnick's own method.

Indexed as

Magnetic Resonance ImagingRestHumanscluster inferencefMRIopen data

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.