Evidence map›Paper›PMID 28139244›Full record

ReviewJournal of neuroimmunology2017

MicroRNA 155 and viral-induced neuroinflammation.

Laura L Dickey, Timothy M Hanley, Thomas B Huffaker, Andrew G Ramstead, Ryan M O'Connell, Thomas E Lane

Abstract readReview
In one paragraph

Review in Journal of neuroimmunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Lung Inflammation Signature in Post-COVID-19 TB Patients.International journal of molecular sciences · 2023
    Article
  6. Article
  7. miRNAs: The Key Regulator of COVID-19 Disease.International journal of cell biology · 2022
    Review
  8. Microglia Polarization: A Novel Target of Exosome for Stroke Treatment.Frontiers in cell and developmental biology · 2022
    Review
  9. Review
  10. Review
  11. MiR-155: An Important Regulator of Neuroinflammation.International journal of molecular sciences · 2021
    Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Microglia Polarization from M1 toward M2 Phenotype Is Promoted byOxidative medicine and cellular longevity · 2021
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Laura L DickeyDepartment of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, United States. Electronic address: laura.dickey@path.utah.edu.
Timothy M HanleyDepartment of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, United States. Electronic address: timothy.hanley@hsc.utah.edu.
Thomas B HuffakerDepartment of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, United States. Electronic address: thomas.huffaker@path.utah.edu.
Andrew G RamsteadDepartment of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, United States. Electronic address: andrew.ramstead@path.utah.edu.
Ryan M O'ConnellDepartment of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, United States. Electronic address: ryan.oconnell@path.utah.edu.
Thomas E LaneDepartment of Pathology, University of Utah School of Medicine, Salt Lake City, UT 84112, United States. Electronic address: tom.lane@path.utah.edu.
University of Utah · US

Funding

Training Program in Microbial PathogenesisT32AI055434 · NIAID · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI MULVEY, MATTHEW A, PLANELLES, VICENTE · 2004 to 2025
$6.0M
Chemokines and Viral-Induced Neurologic DiseaseR01NS041249 · NINDS · UNIVERSITY OF UTAH · PI LANE, THOMAS E · 2002 to 2019
$5.4M
Utilizing TALEN technology to regulate human microRNA'sDP2GM111099 · NIGMS · UNIVERSITY OF UTAH · PI O'CONNELL, RYAN M · 2013 to 2013
$2.2M
Micro RNAs and chronic, low-grade inflammationR01AG047956 · NIA · UNIVERSITY OF UTAH · PI O'CONNELL, RYAN M · 2015 to 2019
$1.7M
NIAID NIH HHS T32 AI055434NIA NIH HHS R01 AG047956NIGMS NIH HHS DP2 GM111099NINDS NIH HHS R01 NS041249
6 · The paper itself

Abstract

MicroRNA (miRNA) regulation of gene expression is becoming an increasingly recognized mechanism by which host immune responses are governed following microbial infection. miRNAs are short, non-coding RNAs that repress translation of target genes, and have been implicated in a number of activities that modulate host immune responses, including the regulation of immune cell proliferation, survival, expansion, differentiation, migration, polarization, and effector function. This review highlights several examples in which mammalian-encoded miR-155 influences immune responses following viral infection of the CNS.

Indexed as

EncephalitisMyelitisAnimalsGene Expression Regulation, ViralHumansMicroRNAsVirus DiseasesMicroRNAsMicroRNAsmiR-155NeuroinflammationNeuropathogenesisNeurotropic viruses

Identifiers

PMID28139244
PMCPMC5821228
OpenAlexW2580396797

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.