Evidence map›Paper›PMID 28139000›Full record

Observational studyHeadache2017

Psychological Factors Associated With Chronic Migraine and Severe Migraine-Related Disability: An Observational Study in a Tertiary Headache Center.

Elizabeth K Seng, Dawn C Buse, Jaclyn E Klepper, Sarah J Mayson, Amy S Grinberg, Brian M Grosberg, Jelena M Pavlovic, Matthew S Robbins, Sarah E Vollbracht, Richard B Lipton

Open access · greenAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Headache, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it, 107 citations in OpenAlex.

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  15. Middle meningeal artery embolization for migraine: A review.Surgical neurology international · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Elizabeth K SengFerkauf Graduate School of Psychology, Yeshiva University, Bronx, NY, USA.
Dawn C BuseFerkauf Graduate School of Psychology, Yeshiva University, Bronx, NY, USA.
Jaclyn E KlepperFerkauf Graduate School of Psychology, Yeshiva University, Bronx, NY, USA.
Sarah J MaysonFerkauf Graduate School of Psychology, Yeshiva University, Bronx, NY, USA.
Amy S GrinbergFerkauf Graduate School of Psychology, Yeshiva University, Bronx, NY, USA.
Brian M GrosbergHartford Healthcare Headache Center, Wethersfield, CT, USA.
Jelena M PavlovicAlbert Einstein College of Medicine, Bronx, NY, USA.
Matthew S RobbinsAlbert Einstein College of Medicine, Bronx, NY, USA.
Sarah E VollbrachtAlbert Einstein College of Medicine, Bronx, NY, USA.
Richard B LiptonAlbert Einstein College of Medicine, Bronx, NY, USA.
Yeshiva University · USAlbert Einstein College of Medicine · USMontefiore Medical Center · USHartford Financial Services (United States)

Funding

Vascular Structure and Function in Cognitive AgingP01AG003949 · NIA · YESHIVA UNIVERSITY · PI CAROL A. DERBY · 1985 to 2026
$73.9M
STATISTICS AND DATA MANAGEMENT COREP01AG027734 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI BERGMAN, AVIV · 2007 to 2012
$9.3M
PREDICTORS OF COGNITIVE DECLINE IN NORMAL AGINGR01AG012101 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DE LEON, MONY J., RUSINEK, HENRY · 1993 to 2015
$6.7M
Biomarkers in Early Alzheimer's Disease (AD).R01AG022374 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DE LEON, MONY J., RUSINEK, HENRY · 2004 to 2015
$5.2M
TWO PRECLINICAL LATENT SCORES TO PREDICT OCCURRENCE OF DATR01AG034119 · NIA · WASHINGTON UNIVERSITY · PI XIONG, CHENGJIE · 2010 to 2014
$1.6M
Latent Mobility Abnormalities And FrailtyR01AG025119 · NIA · ALBERT EINSTEIN COL OF MED YESHIVA UNIV · PI VERGHESE, JOE · 2005 to 2009
$1.5M
Clinical Decision Support for Patient Migraine ManagementK23NS096107 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI SENG-TAMACCIO, ELIZABETH K · 2016 to 2020
$965k
The relation of migraine to daily hormone patterns and menopausal stageK23AG049466 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI PAVLOVIC, JELENA · 2016 to 2021
$918k
Gender and Hormonal Differences in Parkinson's DiseaseK23NS047256 · NINDS · BETH ISRAEL MEDICAL CTR (NEW YORK) · PI SAUNDERS-PULLMAN, RACHEL · 2004 to 2008
$869k
NIA NIH HHS K23 AG049466NIA NIH HHS P01 AG003949NIA NIH HHS P01 AG027734NIA NIH HHS R01 AG012101NIA NIH HHS R01 AG022374NIA NIH HHS R01 AG025119NIA NIH HHS R01 AG034119NINDS NIH HHS K23 NS047256NINDS NIH HHS K23 NS096107
6 · The paper itself

Abstract

objectiveTo evaluate the relationships among modifiable psychological factors and chronic migraine and severe migraine-related disability in a clinic-based sample of persons with migraine.

backgroundEvidence evaluating relationships between modifiable psychological factors and chronic migraine and severe migraine-related disability is lacking in people with migraine presenting for routine clinical care.

methodsAdults with migraine completed surveys during routinely scheduled visits to a tertiary headache center. Participants completed surveys assessing chronic migraine (meeting criteria for migraine with ≥15 headache days in the past month), severe migraine disability (Migraine Disability Assessment Scale score ≥ 21), and modifiable psychological factors (depressive symptoms [Patient Health Questionnaire-9], anxious symptoms [Generalized Anxiety Disorder-7], Pain Catastrophizing Scale and Headache Specific Locus of Control). Logistic regression evaluated relationships between modifiable psychological factors and chronic migraine and severe migraine disability.

resultsAmong 90 eligible participants the mean age was 45.0 (SD = 12.4); 84.8% were women. One-third (36.0%) met study criteria for chronic migraine; half of participants (51.5%) reported severe migraine-related disability. Higher depressive symptoms (OR = 1.99, 95% CI = 1.11, 3.55) and chance HSLC (OR = 1.85, 95% CI = 1.13, 1.43) were associated with chronic migraine. Higher depressive symptoms (OR = 3.54, 95%CI = 1.49, 8.41), anxiety symptoms (OR = 3.65, 95% CI = 1.65, 8.06), and pain catastrophizing (OR = 1.95, 95% CI = 1.14, 3.35), were associated with severe migraine-related disability.

conclusionsPsychiatric symptoms and pain catastrophizing were strongly associated with severe migraine-related disability. Depression and chance locus of control were associated with chronic migraine. This study supports the need for longitudinal observational studies to evaluate the relationships among naturalistic variation in psychological factors, migraine-related disability, and migraine chronification.

Indexed as

Persons with DisabilitiesAdultAgedAvoidance LearningCatastrophizationChronic DiseaseCognitionCultureDisability EvaluationFemaleHealth SurveysHumansMaleMiddle AgedMigraine DisordersMood Disordersanxietycatastrophizingchronic migrainedepressiondisabilitylocus of controlmigraine

Identifiers

PMID28139000
PMCPMC5378650
OpenAlexW2585816301

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.