Evidence map›Paper›PMID 28138844›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2017

Haplotyping a Non-meiotic Diploid Fungal Pathogen Using Induced Aneuploidies and SNP/CGH Microarray Analysis.

Judith Berman, Anja Forche

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Identification, Pathogenicity, and Genetic Diversity ofInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Judith BermanDepartment of Molecular Microbiology & Biotechnology, Tel Aviv University, Ramat Aviv, Israel.
Anja ForcheDepartment of Biology, Bowdoin College, Brunswick, ME, USA. aforche@bowdoin.edu.

Funding

Centromere Structure and Function in Candida albicansR01AI075096 · NIAID · UNIVERSITY OF MINNESOTA · PI BERMAN, JUDITH G. · 2008 to 2012
$2.6M
Role of genome plasticity in Candida albicans host-pathogen interactionsR15AI090633 · NIAID · BOWDOIN COLLEGE · PI FORCHE, ANJA · 2011 to 2018
$1.1M
NIAID NIH HHS R01 AI075096NIAID NIH HHS R15 AI090633
6 · The paper itself

Abstract

The generation of haplotype information has recently become very attractive due to its utility for identifying mutations associated with human disease and for the development of personalized medicine. Haplotype information also is crucial for studying recombination mechanisms and genetic diversity, and for analyzing allele-specific gene expression. Classic haplotyping methods require the analysis of hundreds of meiotic progeny. To facilitate haplotyping in the non-meiotic human fungal pathogen Candida albicans, we exploited trisomic heterozygous chromosomes generated via the UAU1 selection strategy. Using this system, we obtained phasing information from allelic biases, detected by SNP/CGH microarray analysis. This strategy has the potential to be applicable to other diploid, asexual Candida species that are important causes of human disease.

Indexed as

AneuploidyDiploidyCandida albicansGenetic VariationGenome, FungalHaplotypesMeiosisAneuploidyCandida albicansHaplotypingHeterozygosityNon-meiotic organismPhased genomeSNP/CGH microarraysUAU1 cassetteYmap

Identifiers

PMID28138844
PMCPMC5482211

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.