Evidence map›Paper›PMID 28138810›Full record

ArticleLasers in medical science2017

Photobiostimulation reverses allodynia and peripheral nerve damage in streptozotocin-induced type 1 diabetes.

Igor Rafael Correia Rocha, Adriano Polican Ciena, Alyne Santana Rosa, Daniel Oliveira Martins, Marucia Chacur

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Effects of Low-Level Laser Therapy and Purified Natural Latex (International journal of molecular sciences · 2023
    Article
  4. Article
  5. Effect of photobiomodulation on mitochondrial dynamics in peripheral nervous system in streptozotocin-induced type 1 diabetes in rats.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2021
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Igor Rafael Correia RochaDepartment of Anatomy, Biomedical Sciences Institute, University of São Paulo, Av. Prof. Lineu Prestes, 2415, 05508-900, São Paulo, Brazil.
Adriano Polican CienaInstitute of Biosciences, University Estadual Paulista Júlio de Mesquita Filho, Rio Claro, 13506900, São Paulo, Brazil.
Alyne Santana RosaDepartment of Anatomy, Biomedical Sciences Institute, University of São Paulo, Av. Prof. Lineu Prestes, 2415, 05508-900, São Paulo, Brazil.
Daniel Oliveira MartinsDepartment of Anatomy, Biomedical Sciences Institute, University of São Paulo, Av. Prof. Lineu Prestes, 2415, 05508-900, São Paulo, Brazil.
Marucia ChacurDepartment of Anatomy, Biomedical Sciences Institute, University of São Paulo, Av. Prof. Lineu Prestes, 2415, 05508-900, São Paulo, Brazil. chacurm@icb.usp.br.
Universidade de São Paulo · BRUniversidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For better evaluation of the efficacy of low-level laser therapy in treating painful diabetic neuropathy and in protecting nerve fiber damage, we conducted a study with type 1 diabetic rats induced by streptozotocin. It is well known that diabetic peripheral neuropathy is the leading cause of pain in those individuals who suffer from diabetes. Despite the efficacy of insulin in controlling glucose level in blood, there is no effective treatment to prevent or reverse neuropathic damage for total pain relief.Male Wistar rats were divided into saline, vehicle, and treatment groups. A single intraperitoneal (i.p.) injection of streptozotocin (STZ) (85 mg/kg) was administered for the induction of diabetes. The von Frey filaments were used to assess nociceptive thresholds (allodynia). Behavioral measurements were accessed 14, 28, 48, and 56 days after STZ administration. Rats were irradiated with GaAs Laser (Gallium Arsenide, Laserpulse, Ibramed Brazil) emitting a wavelength of 904 nm, an output power of 45 mWpk, beam spot size at target 0.13 cm

Indexed as

AnimalsDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 1Diabetic NeuropathiesHyperalgesiaLasers, SemiconductorLow-Level Light TherapyMalePainRatsRats, WistarStreptozocinStreptozocinDiabetes mellitusMyelin sheathNociceptionRatSciatic nerveStreptozotocin

Identifiers

PMID28138810
OpenAlexW2581386320

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.