Evidence map›Paper›PMID 28138773›Full record

ArticleHuman genetics2017

Revisiting the male genetic landscape of China: a multi-center study of almost 38,000 Y-STR haplotypes.

Michael Nothnagel, Guangyao Fan, Fei Guo, Yongfeng He, Yiping Hou, Shengping Hu, Jiang Huang, Xianhua Jiang, Wook Kim, Kicheol Kim and 31 more

RetractedAbstract readMulticenter StudyRetracted Publication
PubMed Publisher
In one paragraph

Article in Human genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

41 authors.

Michael NothnagelDepartment of Statistical Genetics and Bioinformatics, Cologne Center for Genomics (CCG), University of Cologne, Weyertal 115b, 50931, Cologne, Germany. michael.nothnagel@uni-koeln.de.ORCID http://orcid.org/0000-0001-8305-7114
Guangyao FanDepartment of Public Security Technology, The Center for Forensic Science Research, Railway Police College, Zhengzhou, 450053, People's Republic of China.
Fei GuoDepartment of Forensic Medicine, National Police University of China, Shenyang, 110854, People's Republic of China.
Yongfeng HeDepartment of Criminal Investigation, Shaanxi Provincial Public Security Bureau, Xi'an, 710016, People's Republic of China.
Yiping HouInstitute of Forensic Medicine, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu, 610041, People's Republic of China.
Shengping HuMolecular Biology and Forensic Genetics Laboratory, Shantou University Medical College, Shantou, People's Republic of China.
Jiang HuangDepartment of Forensic Medicine, Guizhou Medical University, Beijing Road, 9th, Guiyang, 550004, People's Republic of China.
Xianhua JiangLiaoning Criminal and Science Technology Research Institute, Shenyang, 110032, People's Republic of China.
Wook KimDepartment of Biological Sciences, Dankook University, Cheonan, 330-714, Republic of Korea.
Kicheol KimDepartment of Neurology, University of California, San Francisco, San Francisco, CA, 94158, USA.
Chengtao LiShanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Institute of Forensic Sciences, Ministry of Justice, P.R. China, Shanghai, 200063, People's Republic of China.
Hui LiMOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, 200438, People's Republic of China.
Liming LiMOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, 200438, People's Republic of China.
Shilin LiMOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, 200438, People's Republic of China.
Zhao LiDepartment of Criminal Investigation, Hebei Provincial Public Security Bureau, Shijiazhuang City, 050000, People's Republic of China.
Weibo LiangInstitute of Forensic Medicine, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu, 610041, People's Republic of China.
Chao LiuGuangzhou Forensic Science Institute, Guangzhou, 510030, People's Republic of China.
Di LuSchool of Forensic Medicine, Kunming Medical University, Kunming, 650500, People's Republic of China.
Haibo LuoInstitute of Forensic Medicine, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu, 610041, People's Republic of China.
Shengjie NieSchool of Forensic Medicine, Kunming Medical University, Kunming, 650500, People's Republic of China.
Meisen ShiCenter of Cooperative Innovation for Judicial Civilization, Institute of Evidence Law and Forensic Science, China University of Political Science and Law, Ministry of Education, Beijing, 100088, People's Republic of China.
Hongyu SunDepartment of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510089, People's Republic of China.
Jianpin TangDepartment of Forensic Medicine, Guangdong Medical University, Dongguan, 523808, People's Republic of China.
Lei WangDepartment of Forensic Sciences, Police Station of Zhengzhou, Zhengzhou, Henan, 450008, People's Republic of China.
Chuan-Chao WangDepartment of Archaeogenetics, Max Planck Institute for the Science of Human History, Jena, Germany.
Dan WangInstitute of Forensic Medicine and Laboratory Medicine, Jining Medical University, Jining, Shandong, People's Republic of China.
Shao-Qing WenMOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, 200438, People's Republic of China.
Hongyan WuXinxiang Medical University School of Basic Medical, Xinxiang, Henan, 453003, People's Republic of China.
Weiwei WuInstitute of Forensic Science, Zhejiang Provincial Public Security Bureau, Hangzhou, 310009, People's Republic of China.
Jiaxin XingSchool of Forensic Medicine, China Medical University, Shenyang, People's Republic of China.
Jiangwei YanBeijing Institute of Genomics, Chinese Academy of Sciences, Beijing, 100101, People's Republic of China.
Shi YanMOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, 200438, People's Republic of China.
Hongbing YaoKey Laboratory of Evidence Science of Gansu Province, Gansu Institute of Political Science and Law, Lanzhou, 730070, People's Republic of China.
Yi YeInstitute of Forensic Medicine, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu, 610041, People's Republic of China.
Libing YunInstitute of Forensic Medicine, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu, 610041, People's Republic of China.
Zhaoshu ZengSchool of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, 450052, People's Republic of China.
Lagabaiyila ZhaForensic Science Department, School of Basic Medical Sciences, Central South University, Changsha, 410013, People's Republic of China.
Suhua ZhangShanghai Key Laboratory of Forensic Medicine, Shanghai Forensic Service Platform, Institute of Forensic Sciences, Ministry of Justice, P.R. China, Shanghai, 200063, People's Republic of China.
Xiufen ZhengDepartment of Pathology, Department of Surgery, Department of Oncology, University of Western Ontario, Lawson Health Research Institute, London, Canada.
Sascha WilluweitDepartment of Forensic Genetics, Institute of Legal Medicine and Forensic Sciences, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Lutz RoewerDepartment of Forensic Genetics, Institute of Legal Medicine and Forensic Sciences, Charité-Universitätsmedizin Berlin, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

China has repeatedly been the subject of genetic studies to elucidate its prehistoric and historic demography. While some studies reported a genetic distinction between Northern and Southern Han Chinese, others showed a more clinal picture of small differences within China. Here, we investigated the distribution of Y chromosome variation along administrative as well as ethnic divisions in the mainland territory of the People's Republic of China, including 28 administrative regions and 19 recognized Chinese nationalities, to assess the impact of recent demographic processes. To this end, we analyzed 37,994 Y chromosomal 17-marker haplotype profiles from the YHRD database with respect to forensic diversity measures and genetic distance between groups defined by administrative boundaries and ethnic origin. We observed high diversity throughout all Chinese provinces and ethnicities. Some ethnicities, including most prominently Kazakhs and Tibetans, showed significant genetic differentiation from the Han and other groups. However, differences between provinces were, except for those located on the Tibetan plateau, less pronounced. This discrepancy is explicable by the sizeable presence of Han speakers, who showed high genetic homogeneity all across China, in nearly all studied provinces. Furthermore, we observed a continuous genetic North-South gradient in the Han, confirming previous reports of a clinal distribution of Y chromosome variation and being in notable concordance with the previously observed spatial distribution of autosomal variation. Our findings shed light on the demographic changes in China accrued by a fast-growing and increasingly mobile population.

Indexed as

HaplotypesAsian PeopleChinaChromosomes, Human, YGenetics, PopulationGenetic VariationGenotyping TechniquesHumansMaleMicrosatellite Repeats

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.