Evidence map›Paper›PMID 28138689›Full record

ArticleJournal of biomedical optics2017

Generation of anatomically realistic numerical phantoms for photoacoustic and ultrasonic breast imaging.

Yang Lou, Weimin Zhou, Thomas P Matthews, Catherine M Appleton, Mark A Anastasio

Open access · goldAbstract read
In one paragraph

Article in Journal of biomedical optics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 113 citations in OpenAlex.

  1. Article
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  3. Article
  4. Article
  5. Review
  6. Advances in Photoacoustic Imaging of Breast Cancer.Sensors (Basel, Switzerland) · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review of imaging test phantoms.Journal of biomedical optics · 2023
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yang LouWashington University in St. Louis, Department of Biomedical Engineering, 1 Brookings Drive, St. Louis, Missouri 63130, United States.
Weimin ZhouWashington University in St. Louis, Department of Electrical and Systems Engineering, 1 Brookings Drive, St. Louis, Missouri 63130, United States.
Thomas P MatthewsWashington University in St. Louis, Department of Biomedical Engineering, 1 Brookings Drive, St. Louis, Missouri 63130, United States.
Catherine M AppletonWashington University in St. Louis, Mallinckrodt Institute of Radiology, 1 Brookings Drive, St. Louis, Missouri 63130, United States.
Mark A AnastasioWashington University in St. Louis, Department of Biomedical Engineering, 1 Brookings Drive, St. Louis, Missouri 63130, United StatesbWashington University in St. Louis, Department of Electrical and Systems Engineering, 1 Brookings Drive, St. Louis, Missouri 63130, United StatescWashington University in St. Louis, Mallinckrodt Institute of Radiology, 1 Brookings Drive, St. Louis, Missouri 63130, United States.
Washington University in St. Louis · USMallinckrodt (United States) · US

Funding

Multimode laser optoacoustic tomography system for breast cancer careR01CA167446 · NCI · TOMOWAVE LABORATORIES, INC. · PI ORAEVSKY, ALEXANDER A · 2012 to 2016
$2.5M
NCI NIH HHS R01 CA167446
6 · The paper itself

Abstract

Photoacoustic computed tomography (PACT) and ultrasound computed tomography (USCT) are emerging modalities for breast imaging. As in all emerging imaging technologies, computer-simulation studies play a critically important role in developing and optimizing the designs of hardware and image reconstruction methods for PACT and USCT. Using computer-simulations, the parameters of an imaging system can be systematically and comprehensively explored in a way that is generally not possible through experimentation. When conducting such studies, numerical phantoms are employed to represent the physical properties of the patient or object to-be-imaged that influence the measured image data. It is highly desirable to utilize numerical phantoms that are realistic, especially when task-based measures of image quality are to be utilized to guide system design. However, most reported computer-simulation studies of PACT and USCT breast imaging employ simple numerical phantoms that oversimplify the complex anatomical structures in the human female breast. We develop and implement a methodology for generating anatomically realistic numerical breast phantoms from clinical contrast-enhanced magnetic resonance imaging data. The phantoms will depict vascular structures and the volumetric distribution of different tissue types in the breast. By assigning optical and acoustic parameters to different tissue structures, both optical and acoustic breast phantoms will be established for use in PACT and USCT studies.

Indexed as

Tomography, X-Ray ComputedAlgorithmsBreastComputer SimulationFemaleHumansImage Processing, Computer-AssistedPhantoms, Imaging

Identifiers

PMID28138689
PMCPMC5282404
OpenAlexW2584507399

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.