ArticleWorld journal of clinical cases2017
Local advanced rectal cancer perforation in the midst of preoperative chemoradiotherapy: A case report and literature review.
Article in World journal of clinical cases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 7 citations in OpenAlex.
- Imaging of anorectal and perineal emergencies - a multimodality review.Emergency radiology · 2026Review
- Emergency rectal cancer: clinical presentation and therapeutic options.Frontiers in surgery · 2026Article
- Successful resection of rectal cancer and perirectal abscess following systemic chemotherapy and chemoradiotherapy: A case report.International journal of surgery case reports · 2023Article
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Authors and funding
15 authors at 5 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
Standard chemoradiotherapy (CRT) for local advanced rectal cancer (LARC) rarely induce rectal perforation. Here we report a rare case of rectal perforation in a patient with LARC in the midst of preoperative CRT. A 56-year-old male was conveyed to our hospital exhibiting general malaise. Colonoscopy and imaging tests resulted in a clinical diagnosis of LARC with direct invasion to adjacent organs and regional lymphadenopathy. Preoperative 5-fluorouracil-based CRT was started. At 25 d after the start of CRT, the patient developed a typical fever. Computed tomography revealed rectal perforation, and he underwent emergency sigmoid colostomy. At 12 d after the surgery, the remaining CRT was completed according to the original plan. The histopathological findings after radical operation revealed a wide field of tumor necrosis and fibrosis without lymph node metastasis. We share this case as important evidence for the treatment of LARC perforation in the midst of preoperative CRT.
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