Evidence map›Paper›PMID 28138436›Full record

ReviewClinical and translational imaging2017

Siderophores for molecular imaging applications.

Milos Petrik, Chuangyan Zhai, Hubertus Haas, Clemens Decristoforo

Open access · hybridAbstract readReview
In one paragraph

Review in Clinical and translational imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 128 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Automated Production of [Pharmaceutics · 2024
    Article
  9. [ACS infectious diseases · 2024
    Article
  10. Review
  11. Review
  12. Article
  13. Siderophores as tools and treatments.npj antimicrobials and resistance · 2024
    Review
  14. Review
  15. Article
  16. Nobachelins, new siderophores fromSynthetic and systems biotechnology · 2023
    Article
  17. Article
  18. Review
  19. Review
  20. Structural Requirements for GaInorganic chemistry · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Milos Petrik0000 0001 1245 3953grid.10979.36Faculty of Medicine and Dentistry, Institute of Molecular and Translational Medicine, Palacky University, Olomouc, Czech Republic.
Chuangyan Zhai0000 0000 8853 2677grid.5361.1Universitätsklinik für Nuklearmedizin, Medizinische Universität Innsbruck, Anichstr. 35, 6020 Innsbruck, Austria ; 0000 0000 8653 1072grid.410737.6Department of Experimental Nuclear Medicine, Guangzhou Medical University, Guangzhou, Guangdong China.
Hubertus Haas0000 0000 8853 2677grid.5361.1Division of Molecular Biology, Biocenter, Medical University Innsbruck, Innsbruck, Austria.
Clemens Decristoforo0000 0000 8853 2677grid.5361.1Universitätsklinik für Nuklearmedizin, Medizinische Universität Innsbruck, Anichstr. 35, 6020 Innsbruck, Austria.ORCID 0000-0003-0566-4036
Innsbruck Medical University · ATInstitute of Molecular and Translational Medicine · CZ

Funding

Austrian Science Fund FWF L 676Austrian Science Fund FWF P 25899
6 · The paper itself

Abstract

This review covers publications on siderophores applied for molecular imaging applications, mainly for radionuclide-based imaging. Siderophores are low molecular weight chelators produced by bacteria and fungi to scavenge essential iron. Research on these molecules has a continuing history over the past 50 years. Many biomedical applications have been developed, most prominently the use of the siderophore desferrioxamine (DFO) to tackle iron overload related diseases. Recent research described the upregulation of siderophore production and transport systems during infection. Replacing iron in siderophores by radionuclides, the most prominent Ga-68 for PET, opens approaches for targeted imaging of infection; the proof of principle has been reported for fungal infections using

Indexed as

Bifunctional chelatorDesferrioxamineInfectionSiderophoresTriacetylfusarinine C

Identifiers

PMID28138436
PMCPMC5269471
OpenAlexW2530663934

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.