Evidence map›Paper›PMID 28138401›Full record

ArticleThe journal of pathology. Clinical research2017

T-cadherin in prostate cancer: relationship with cancer progression, differentiation and drug resistance.

Boris Dasen, Tatjana Vlajnic, Chantal Mengus, Christian Ruiz, Lukas Bubendorf, Giulio Spagnoli, Stephen Wyler, Paul Erne, Thérèse J Resink, Maria Philippova

Open access · goldAbstract read
In one paragraph

Article in The journal of pathology. Clinical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. CaAntibodies (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Boris DasenDepartment of Biomedicine, Laboratory for Signal Transduction University Hospital Basel Switzerland.
Tatjana VlajnicInstitute of Pathology, University Hospital Basel Switzerland.
Chantal MengusInstitute of Surgical Research and Department of Biomedicine Basel University Hospital Switzerland.
Christian RuizInstitute of Pathology, University Hospital Basel Switzerland.
Lukas BubendorfInstitute of Pathology, University Hospital Basel Switzerland.
Giulio SpagnoliInstitute of Surgical Research and Department of Biomedicine Basel University Hospital Switzerland.
Stephen WylerUrology Clinic, University Hospital Basel Switzerland.
Paul ErneDepartment of Biomedicine, Laboratory for Signal Transduction University Hospital Basel Switzerland.
Thérèse J ResinkDepartment of Biomedicine, Laboratory for Signal Transduction University Hospital Basel Switzerland.
Maria PhilippovaDepartment of Biomedicine, Laboratory for Signal Transduction University Hospital Basel Switzerland.
University Hospital of Basel · CHDepartment of Biomedicine Basel · CHUniversity of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer represents the second leading cause of cancer-related death in men. T-cadherin (CDH13) is an atypical GPI-anchored member of the cadherin family of adhesion molecules. Its gene was reported to be downregulated in a small series of prostate tumours. T-cadherin protein expression/localisation in prostate tissue has never been investigated. The purpose of our study was to analyse CDH13 gene and protein levels in large sets of healthy and cancer prostate tissue specimens and evaluate CDH13 effects on the sensitivity of prostate cancer cells to chemotherapy. Analysis of CDH13 gene expression in the TCGA RNAseq dataset for prostate adenocarcinoma (

Indexed as

basal and luminal cellscadherinsdoxorubicindrug resistanceprostate cancerT‐cadherin

Identifiers

PMID28138401
PMCPMC5259566
OpenAlexW2543036618

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.