Evidence map›Paper›PMID 28138319›Full record

ArticleFrontiers in psychiatry2016

Feasibility and Preliminary Efficacy of a Novel RDoC-Based Treatment Program for Adolescent Depression: "Training for Awareness Resilience and Action" (TARA)-A Pilot Study.

Eva Henje Blom, Olga Tymofiyeva, Margaret A Chesney, Tiffany C Ho, Patricia Moran, Colm G Connolly, Larissa G Duncan, Lisa Baldini, Helen Y Weng, Michael Acree and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Single-arm Pilot Trial of Hatha Yoga for Adolescents with Depression.Evidence-based practice in child and adolescent mental health · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Empirically supported interventions in psychology: contributions of Research Domain Criteria.Psicologia, reflexao e critica : revista semestral do Departamento de Psicologia da UFRGS · 2019
    Review
  19. Article
  20. Developmental Psychopathology and the Research Domain Criteria: Friend or Foe?Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Eva Henje BlomDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Department of Clinical Sciences, Umeå Universitet, Umeå, Sweden; Department of Psychiatry, Division of Child and Adolescent Psychiatry, UCSF Weill Institute for Neurosciences, University of California San Francisco (UCSF), San Francisco, CA, USA.
Olga TymofiyevaDepartment of Radiology, University of California San Francisco (UCSF) , San Francisco, CA , USA.
Margaret A ChesneyThe Osher Center for Integrative Medicine, University of California San Francisco (UCSF) , San Francisco, CA , USA.
Tiffany C HoNeurosciences Program, Department of Psychology, Stanford University , Stanford, CA , USA.
Patricia MoranThe Osher Center for Integrative Medicine, University of California San Francisco (UCSF) , San Francisco, CA , USA.
Colm G ConnollyDepartment of Psychiatry, Division of Child and Adolescent Psychiatry, UCSF Weill Institute for Neurosciences, University of California San Francisco (UCSF) , San Francisco, CA , USA.
Larissa G DuncanDepartment of Human Development and Family Studies, Center for Healthy Minds, University of Wisconsin-Madison, Madison, WI, USA; Department of Family Medicine and Community Health, Center for Healthy Minds, University of Wisconsin-Madison, Madison, WI, USA.
Lisa BaldiniNeurosciences Program, Department of Psychology, Stanford University , Stanford, CA , USA.
Helen Y WengThe Osher Center for Integrative Medicine, University of California San Francisco (UCSF) , San Francisco, CA , USA.
Michael AcreeThe Osher Center for Integrative Medicine, University of California San Francisco (UCSF) , San Francisco, CA , USA.
Veronica GoldmanThe Osher Center for Integrative Medicine, University of California San Francisco (UCSF) , San Francisco, CA , USA.
Frederick M HechtThe Osher Center for Integrative Medicine, University of California San Francisco (UCSF) , San Francisco, CA , USA.
Tony T YangDepartment of Psychiatry, Division of Child and Adolescent Psychiatry, UCSF Weill Institute for Neurosciences, University of California San Francisco (UCSF) , San Francisco, CA , USA.
University of California, San Francisco · USStanford University · USUniversity of Wisconsin–Madison · US

Funding

Training Researchers in Clinical Integrative Medicine (TRIM) - NOSI supplementT32AT003997 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SHELLEY R ADLER, MARIA T CHAO · 2007 to 2026
$6.6M
A Cross-Sectional and Longitudinal Functional MRI Study of Adolescent DepressionR01MH085734 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI YANG, TONY TUNG-I · 2010 to 2014
$2.7M
Mentoring and Research in Integrative MedicineK24AT007827 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HECHT, FREDERICK M · 2013 to 2022
$1.8M
NCCIH NIH HHS K24 AT007827NCCIH NIH HHS T32 AT003997NIMH NIH HHS R01 MH085734
6 · The paper itself

Abstract

backgroundThe novel group treatment program Training for Awareness, Resilience, and Action (TARA) was developed to target specific mechanisms based on neuroscience findings in adolescent depression and framed within the National Institute of Mental Health Research Domain Criteria. TARA contains training of autonomic and emotional self-regulation, interoceptive awareness, relational skills, and value-based committed action.

methodsWe performed a single-arm trial to test the feasibility and preliminary efficacy of TARA in reducing depression and anxiety levels and assessed whether the specific targeted domains of function reflected the hypothesized symptom change. Twenty-six adolescents (14-18 years old, 7 males and 19 females) participated in the 12-week group program. Assessment was performed before (T0), immediately after (T1), and 3 months after the end of TARA (T2).

resultsSignificant improvement was seen in depression symptoms (Reynolds Adolescent Depression Scale Second Edition) between T0-T1 ( LIMITATIONS: The sample size was small without a control condition. The pilot design did not allow for testing the hypothesized brain changes and effect of TARA on relevant systemic biomarkers.

conclusionTARA is feasible in a sample of clinically depressed and/or anxious adolescents and preliminary efficacy was demonstrated by reduced depression and anxiety symptoms. The specific symptom and behavioral outcomes corresponded well with the hypothesized mechanisms of change.

Indexed as

adolescent depressionautonomic regulationemotion regulationmindfulness-basednon-pharmacologicalnovel treatment developmentResearch Domain Criteria (RDoC)yoga-based

Identifiers

PMID28138319
PMCPMC5237634
OpenAlexW2571821663

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.