Evidence map›Paper›PMID 28138156›Full record

ReviewImmunology and cell biology2017

Antibody-dependent cell cytotoxicity: immunotherapy strategies enhancing effector NK cells.

Maria Carmen Ochoa, Luna Minute, Inmaculada Rodriguez, Saray Garasa, Elisabeth Perez-Ruiz, Susana Inogés, Ignacio Melero, Pedro Berraondo

Open access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Immunology and cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 132 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
132citing papers in PubMed, 1 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

132 citing papers in PubMed, 1 synthesis or guideline pooled it, 219 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  13. Cancer therapy via neoepitope-specific monoclonal antibody cocktails.Cancer immunology, immunotherapy : CII · 2025
    Article
  14. Review
  15. Article
  16. Article
  17. Innate Immune Response to Viral Infection.Advances in experimental medicine and biology · 2025
    Review
  18. Review
  19. Article
  20. Review

72 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Maria Carmen OchoaProgram of Immunology and Immunotherapy, Center for Applied Medical Research (CIMA), Pamplona, Spain.
Luna MinuteProgram of Immunology and Immunotherapy, Center for Applied Medical Research (CIMA), Pamplona, Spain.
Inmaculada RodriguezProgram of Immunology and Immunotherapy, Center for Applied Medical Research (CIMA), Pamplona, Spain.
Saray GarasaProgram of Immunology and Immunotherapy, Center for Applied Medical Research (CIMA), Pamplona, Spain.
Elisabeth Perez-RuizDepartment of Medical Oncology (REDISSEC), Hospital Costa del Sol, Marbella, Spain.
Susana InogésProgram of Immunology and Immunotherapy, Center for Applied Medical Research (CIMA), Pamplona, Spain.
Ignacio MeleroProgram of Immunology and Immunotherapy, Center for Applied Medical Research (CIMA), Pamplona, Spain.
Pedro BerraondoProgram of Immunology and Immunotherapy, Center for Applied Medical Research (CIMA), Pamplona, Spain.
Chartered Institute of Management Accountants · GBNavarre Institute of Health Research · ESHospital Costa del Sol · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibody-dependent cellular cytotoxicity (ADCC) is a set of mechanisms that target cells coated with IgG antibodies of the proper subclasses (IgG1 in the human) to be the prey of cell-to-cell cytolysis executed by immune cells expressing FcRIIIA (CD16A). These effectors include not only natural killer (NK) cells but also other CD16

Indexed as

AnimalsAntibody AffinityAntibody-Dependent Cell CytotoxicityAntigens, NeoplasmCytokinesHumansImmunotherapy, AdoptiveKiller Cells, NaturalMacrophagesMolecular Targeted TherapyNeoplasmsReceptors, Antigen, T-Cell, gamma-deltaReceptors, IgGT-LymphocytesToll-Like ReceptorsAntigens, NeoplasmCytokinesFCGR3A protein, humanReceptors, Antigen, T-Cell, gamma-deltaReceptors, IgGToll-Like Receptors

Identifiers

PMID28138156
OpenAlexW2585754738

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.