Evidence map›Paper›PMID 28138128›Full record

ReviewNature reviews. Nephrology2017

Understanding and preventing contrast-induced acute kidney injury.

Michael Fähling, Erdmann Seeliger, Andreas Patzak, Pontus B Persson

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07294911 (Predictors of Contrast-Induced Acute Kidney Injury in Patients With Acute Coronary Syndrome), which is not on this map. Cited by 158 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
158citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07294911 completednot on this mapstarted 2024, after this paper: background citation

Predictors of Contrast-Induced Acute Kidney Injury in Patients With Acute Coronary Syndrome

TypeobservationalSponsorKaraganda Medical UniversityRan2024 to 2025Enrolled88ConditionsAcute Coronary Syndrome, Contrast-Induced Acute Kidney InjuryArmsObservational data collection
3 · Its place in the literature

Who cites it

158 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Article
  14. Lower AKI Risk and Higher Survival With Microaxial Flow Pump Support During Elective PCI: A Propensity Score-Matched Study.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Observational
  15. Review
  16. Article
  17. Article
  18. Article
  19. BPGM shapes NFAT5-driven cellular responses.Cellular and molecular life sciences : CMLS · 2026
    Article
  20. Article

98 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michael FählingCharité - Universitätsmedizin Berlin, Institut für Vegetative Physiologie, Charitéplatz 1, Berlin, D-10117, Germany.
Erdmann SeeligerCharité - Universitätsmedizin Berlin, Institut für Vegetative Physiologie, Charitéplatz 1, Berlin, D-10117, Germany.
Andreas PatzakCharité - Universitätsmedizin Berlin, Institut für Vegetative Physiologie, Charitéplatz 1, Berlin, D-10117, Germany.
Pontus B PerssonCharité - Universitätsmedizin Berlin, Institut für Vegetative Physiologie, Charitéplatz 1, Berlin, D-10117, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Contrast-induced acute kidney injury (CIAKI) occurs in up to 30% of patients who receive iodinated contrast media and is generally considered to be the third most common cause of hospital-acquired AKI. Accurate assessment of the incidence of CIAKI is obscured, however, by the use of various definitions for diagnosis, the different populations studied and the prophylactic measures put in place. A deeper understanding of the mechanisms that underlie CIAKI is required to enable reliable risk assessment for individual patients, as their medical histories will determine the specific pathways by which contrast media administration might lead to kidney damage. Here, we highlight common triggers that prompt the development of CIAKI and the subsequent mechanisms that ultimately cause kidney damage. We also discuss effective protective measures, such as rapidly acting oral hydration schemes and loop diuretics, in the context of CIAKI pathophysiology. Understanding of how CIAKI arises in different patient groups could enable a marked reduction in incidence and improved outcomes. The ultimate goal is to shape CIAKI prevention strategies for individual patients.

Indexed as

Acute Kidney InjuryContrast MediaFluid TherapyHumansContrast Media

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.