Evidence map›Paper›PMID 28138073›Full record

ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2017

The parable of the caveman and the Ferrari: protein synthesis and the RNA world.

Harry F Noller

Abstract readReview
In one paragraph

Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Perspectives on the ribosome.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Harry F NollerCenter for Molecular Biology of RNA, University of California at Santa Cruz, Santa Cruz, CA 95064, USA noller@biology.ucsc.edu.

Funding

Ribosome Structure and FunctionR35GM118156 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI NOLLER, HARRY F · 2016 to 2025
$7.8M
CRYSTAL STRUCTURE OF THE RIBOSOMER01GM059140 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI NOLLER, HARRY F · 1999 to 2015
$7.2M
RIBOSOME STRUCTURE AND FUNCTIONR01GM017129 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI NOLLER, HARRY F · 1985 to 2015
$6.9M
RIBOSOME STRUCTURE AND FUNCTIONR37GM017129 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI NOLLER, HARRY F · 1990 to 1999
–
NIGMS NIH HHS R01 GM017129NIGMS NIH HHS R01 GM059140NIGMS NIH HHS R35 GM118156NIGMS NIH HHS R37 GM017129
6 · The paper itself

Abstract

The basic steps of protein synthesis are carried out by the ribosome, a very large and complex ribonucleoprotein particle. In keeping with its proposed emergence from an RNA world, all three of its core mechanisms-aminoacyl-tRNA selection, catalysis of peptide bond formation and coupled translocation of mRNA and tRNA-are embodied in the properties of ribosomal RNA, while its proteins play a supportive role.This article is part of the themed issue 'Perspectives on the ribosome'.

Indexed as

Protein BiosynthesisTransfer RNA AminoacylationTranslocation, GeneticOrigin of LifeRNARNAprotein synthesisribosomeRNA

Identifiers

PMID28138073
PMCPMC5311931

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.