Evidence map›Paper›PMID 28138067›Full record

ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2017

Structure and dynamics of bacterial ribosome biogenesis.

Joseph H Davis, James R Williamson

Abstract readReview
In one paragraph

Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed.

  1. Article
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  8. Mechanistic insights intobioRxiv : the preprint server for biology · 2026
    Article
  9. Mechanistic insights into 50Science advances · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
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  18. Article
  19. Review
  20. Article

23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Joseph H DavisDepartment of Integrative Structural and Computational Biology, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.ORCID 0000-0002-8858-8907
James R WilliamsonDepartment of Integrative Structural and Computational Biology, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA jrwill@scripps.edu.ORCID 0000-0002-8772-468X

Funding

Quantitation and biochemical characterization of autophagy's role in agingR00AG050749 · NIA · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI DAVIS, JOSEPH HARRY · 2017 to 2019
$744k
Quantitation and biochemical characterization of autophagy's role in agingK99AG050749 · NIA · SCRIPPS RESEARCH INSTITUTE, THE · PI DAVIS, JOSEPH HARRY · 2015 to 2016
$257k
NIA NIH HHS K99 AG050749NIA NIH HHS R00 AG050749
6 · The paper itself

Abstract

Bacterial ribosome biogenesis has been an active area of research for more than 30 years and has served as a test-bed for the development of new biochemical, biophysical and structural techniques to understand macromolecular assembly generally. Recent work inspecting the process in vivo has advanced our understanding of the role of ribosome biogenesis factors, the co-transcriptional nature of assembly, the kinetics of the process under sub-optimal conditions, and the rRNA folding and ribosome protein binding pathways. Additionally, new structural work enabled by single-particle electron microscopy has helped to connect in vitro ribosomal protein binding maps to the underlying RNA. This review summarizes the state of these in vivo studies, provides a kinetic model for ribosome assembly under sub-optimal conditions, and describes a framework to compare newly emerging assembly intermediate structures.This article is part of the themed issue 'Perspectives on the ribosome'.

Indexed as

Bacterial Physiological PhenomenaOrganelle BiogenesisRibosomesRNA, BacterialRNA, RibosomalRNA, BacterialRNA, Ribosomalassembly factorscryo-electron microscopymacromolecular assemblyquantitative mass spectrometryribosome assemblyRNA folding

Identifiers

PMID28138067
PMCPMC5311925

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.