ArticleDevelopment (Cambridge, England)2017
Integrins are required for tissue organization and restriction of neurogenesis in regenerating planarians.
Article in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 45 citations in OpenAlex.
- Combinatorial mechanisms specify cellular location and neurotransmitter identity during planarian neurogenesis.Nature communications · 2026Article
- Enhanced cell contact and planarian tissue extract increase DNA replication and viability for neoblast cultivation.iScience · 2026Article
- Article
- Knockdown of Atg1 Impairs Brain Regeneration and Downregulates ECM-Related Genes in the Planarian Dugesia japonica.Molecular neurobiology · 2025Article
- map3k1 suppresses terminal differentiation of migratory eye progenitors in planarian regeneration.PLoS genetics · 2025Article
- Article
- A PAK family kinase and the Hippo/Yorkie pathway modulate WNT signaling to functionally integrate body axes during regeneration.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Fate specification is spatially intermingled across planarian stem cells.Nature communications · 2023Article
- BMP suppresses WNT to integrate patterning of orthogonal body axes in adult planarians.PLoS genetics · 2023Article
- BMP suppresses WNT to integrate patterning of orthogonal body axes in adult planarians.bioRxiv : the preprint server for biology · 2023Article
- Combining Fluorescent In Situ Hybridization with Immunofluorescence and Lectin Staining in Planarians.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Positional Information and Stem Cells Combine to Result in Planarian Regeneration.Cold Spring Harbor perspectives in biology · 2022Review
- Restoration of DNA integrity and the cell cycle by electric stimulation in planarian tissues damaged by ionizing radiation.Journal of cell science · 2022Article
- Src acts with WNT/FGFRL signaling to pattern the planarian anteroposterior axis.Development (Cambridge, England) · 2022Article
- Planarian stem cells specify fate yet retain potency during the cell cycle.Cell stem cell · 2021Article
- miR-8b is involved in brain and eye regeneration of Dugesia japonica in head regeneration.Biology open · 2021Article
- Collagen IV differentially regulates planarian stem cell potency and lineage progression.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Decellularization Enables Characterization and Functional Analysis of Extracellular Matrix in Planarian Regeneration.Molecular & cellular proteomics : MCP · 2021Article
- An integrin-binding array platform identifies αJournal of neuroscience methods · 2020Article
- Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tissue regeneration depends on proliferative cells and on cues that regulate cell division, differentiation, patterning and the restriction of these processes once regeneration is complete. In planarians, flatworms with high regenerative potential, muscle cells express some of these instructive cues. Here, we show that members of the integrin family of adhesion molecules are required for the integrity of regenerating tissues, including the musculature. Remarkably, in regenerating
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.