Evidence map›Paper›PMID 28137889›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Genetic variant rs763361 regulates multiple sclerosis CD226 gene expression.

Guiyou Liu, Yang Hu, Shuilin Jin, Qinghua Jiang

Abstract readLetterComment
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Natural killer cells in multiple sclerosis: foe or friends?Frontiers in cellular neuroscience · 2025
    Review
  4. Review
  5. Impact of the Multiple Sclerosis-Associated Genetic VariantNeurology(R) neuroimmunology & neuroinflammation · 2024
    Article
  6. Review
  7. Article
  8. Observational
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Genomic Variation Prediction: A Summary From Different Views.Frontiers in cell and developmental biology · 2021
    Review
  18. Article
  19. Article
  20. Mendelian randomization study to evaluate the effects of interleukin-6 signaling on four neurodegenerative diseases.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Guiyou LiuSchool of Life Science and Technology, Harbin Institute of Technology, Harbin, Heilongjiang 150001, China.
Yang HuSchool of Life Science and Technology, Harbin Institute of Technology, Harbin, Heilongjiang 150001, China.
Shuilin JinDepartment of Mathematics, School of Science, Harbin Institute of Technology, Harbin, Heilongjiang 150001, China.
Qinghua JiangSchool of Life Science and Technology, Harbin Institute of Technology, Harbin, Heilongjiang 150001, China; qhjiang@hit.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetic Predisposition to DiseaseMultiple SclerosisAntigens, Differentiation, T-LymphocyteGenetic VariationHumansAntigens, Differentiation, T-Lymphocyte

Identifiers

PMID28137889
PMCPMC5307472

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.