Evidence map›Paper›PMID 28137804›Full record

ArticleAntimicrobial agents and chemotherapy2017

A Clostridium difficile Lineage Endemic to Costa Rican Hospitals Is Multidrug Resistant by Acquisition of Chromosomal Mutations and Novel Mobile Genetic Elements.

Gabriel Ramírez-Vargas, Carlos Quesada-Gómez, Luis Acuña-Amador, Diana López-Ureña, Tatiana Murillo, María Del Mar Gamboa-Coronado, Esteban Chaves-Olarte, Nicholas Thomson, Evelyn Rodríguez-Cavallini, César Rodríguez

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Mobilome of Environmental Isolates ofAntibiotics (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Genetic Mechanisms of Vancomycin Resistance inAntibiotics (Basel, Switzerland) · 2022
    Review
  5. Mechanisms of antibiotic resistance of Clostridioides difficile.The Journal of antimicrobial chemotherapy · 2021
    Review
  6. Article
  7. High Prevalence of Multidrug-ResistantFrontiers in cellular and infection microbiology · 2020
    Article
  8. Antimicrobial agents and chemotherapy · 2019
    Article
  9. First genotypic characterization of toxigenic Clostridioides difficile in Lithuanian hospitals reveals the prevalence of the hypervirulent ribotype 027/ST1.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gabriel Ramírez-VargasLaboratorio de Investigación en Bacteriología Anaerobia, Centro de Investigación en Enfermedades Tropicales and Facultad de Microbiología,Universidad de Costa Rica, San José, Costa Rica.
Carlos Quesada-GómezLaboratorio de Investigación en Bacteriología Anaerobia, Centro de Investigación en Enfermedades Tropicales and Facultad de Microbiología,Universidad de Costa Rica, San José, Costa Rica.
Luis Acuña-AmadorLaboratorio de Investigación en Bacteriología Anaerobia, Centro de Investigación en Enfermedades Tropicales and Facultad de Microbiología,Universidad de Costa Rica, San José, Costa Rica.
Diana López-UreñaLaboratorio de Investigación en Bacteriología Anaerobia, Centro de Investigación en Enfermedades Tropicales and Facultad de Microbiología,Universidad de Costa Rica, San José, Costa Rica.
Tatiana MurilloLaboratorio de Investigación en Bacteriología Anaerobia, Centro de Investigación en Enfermedades Tropicales and Facultad de Microbiología,Universidad de Costa Rica, San José, Costa Rica.
María Del Mar Gamboa-CoronadoLaboratorio de Investigación en Bacteriología Anaerobia, Centro de Investigación en Enfermedades Tropicales and Facultad de Microbiología,Universidad de Costa Rica, San José, Costa Rica.
Esteban Chaves-OlarteLaboratorio de Investigación en Bacteriología Anaerobia, Centro de Investigación en Enfermedades Tropicales and Facultad de Microbiología,Universidad de Costa Rica, San José, Costa Rica.
Nicholas ThomsonPathogen Genomics, Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom.
Evelyn Rodríguez-CavalliniLaboratorio de Investigación en Bacteriología Anaerobia, Centro de Investigación en Enfermedades Tropicales and Facultad de Microbiología,Universidad de Costa Rica, San José, Costa Rica.
César RodríguezLaboratorio de Investigación en Bacteriología Anaerobia, Centro de Investigación en Enfermedades Tropicales and Facultad de Microbiología,Universidad de Costa Rica, San José, Costa Rica cesar.rodriguezsanchez@ucr.ac.cr.ORCID 0000-0001-5599-0652

Funding

Wellcome Trust 098051
6 · The paper itself

Abstract

The antimicrobial resistance (AMR) rates and levels recorded for

Indexed as

Endemic DiseasesGenome, BacterialInterspersed Repetitive SequencesMutationAnti-Bacterial AgentsClostridioides difficileClostridium InfectionsCosta RicaDNA-Directed RNA PolymerasesDNA GyraseDrug Resistance, Multiple, BacterialGene ExpressionGene Transfer, HorizontalGenotypeHigh-Throughput Nucleotide SequencingHospitalsAnti-Bacterial AgentsDNA-Directed RNA PolymerasesDNA GyraseMetronidazoleVancomycinClostridium difficilecomparative genomicsmultidrug resistanceNAPCR1

Identifiers

PMID28137804
PMCPMC5365686

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.